Abstract
The response to dexamethasone suppression test (DST) in 13 subjects suffering from migraine without aura with coexisting chronic tension type headache, and abusing of instant-relief drugs was studied before and after analgesic withdrawal. Seventy-six per cent of the subjects was found to be non suppressor when abuser and 36% of them maintained the same response to DST after analgesic wash-out. These latter subjects showed a mild degree of depression and a daily pattern of plasma cortisol similar to that reported for depressed patients. These results suggest that in some patients headache and mood disorders coexist, possibly linked to a common psychobiological trait.
| Original language | English |
|---|---|
| Pages (from-to) | 401-407 |
| Number of pages | 7 |
| Journal | Neuroendocrinology Letters |
| Volume | 12 |
| Issue number | 5 |
| Publication status | Published - 1990 |
ASJC Scopus subject areas
- Endocrinology
- Neuroscience(all)