Interessamento epatico in corso di febbre bottonosa del Mediterraneo

Translated title of the contribution: Abnormal liver function in Mediterranean spotted fever

Anna Micalizzi, Emanuele La Spada, Sveva Corsale, Angela Arculeo, Monica La Spada, Pasquale Ouartararo, Lydia Giannitrapani, Maurizio Soresi, Mario Affronti, Giuseppe Montalto

Research output: Contribution to journalArticlepeer-review

Abstract

In this study we retrospectively assessed the prevalence of impaired liver function in all 49 patients suffering from Mediterranean Spotted Fever (MSF) consecutively admitted to our department over the last four years. The main parameters of liver function and ultrasound of upper abdomen were performed at entry and at the end of treatment. At admission mean values of transaminases were above the normal limits and significantly higher when compared to mean serum levels at recovery. 55% and 51% of patients had serum values of GOT and GPT, respectively, above the normal limits versus 1% and 2% at the end of treatment. Mean serum values of alkaline phosphatase (AP) were within the normal limits at entry in hospital, but 22 of them had serum values above the normal limits. The same proportion was seen for gamma glutamiltranspeptidase values. Eighteen patients (36.7%) had both transaminases and AP above the normal limits. There were no significant differences among serum values of albumin, bilirubin and gamma globulin before and after therapy. Platelet count, on the contrary, was significantly reduced at admission (p

Translated title of the contributionAbnormal liver function in Mediterranean spotted fever
Original languageItalian
Pages (from-to)105-110
Number of pages6
JournalInfezioni in Medicina
Volume15
Issue number2
Publication statusPublished - Jun 2007

ASJC Scopus subject areas

  • Microbiology (medical)

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