Abstract
The aim of this study was to investigate the cerebrovascular adaptability to 2 sequential pressor stimuli in elderly patients with isolated systolic hypertension. Ten healthy elderly normotensive subjects (68 to 82 years), 10 elderly subjects with isolated systolic hypertension (63 to 82 years), and 10 young normotensive subjects (24 to 40 years) took part in the study. A pressor reaction, using sequential cold pressor and handgrip stimulation, was induced. The cerebrovascular response to the pressor stimulation was measured by transcranial Doppler determination of the mean flow velocity in the middle cerebral arteries. In all of the subjects, blood pressure increased during handgrip (+12 mm Hg, P
| Original language | English |
|---|---|
| Pages (from-to) | 1143-1150 |
| Number of pages | 8 |
| Journal | Hypertension |
| Volume | 48 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Dec 2006 |
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Keywords
- Adrenergic stimulation
- Cerebrovascular adaptability
- Isolated systolic hypertension
ASJC Scopus subject areas
- Internal Medicine
Cite this
Abnormal pressure passive dilatation of cerebral arterioles in the elderly with isolated systolic hypertension. / Castellani, Sergio; Bacci, Marzia; Ungar, Andrea; Prati, Patrizio; Di Serio, Claudia; Geppetti, Pierangelo; Masotti, Giulio; Serneri, Gian Gastone Neri; Gensini, Gian Franco.
In: Hypertension, Vol. 48, No. 6, 12.2006, p. 1143-1150.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Abnormal pressure passive dilatation of cerebral arterioles in the elderly with isolated systolic hypertension
AU - Castellani, Sergio
AU - Bacci, Marzia
AU - Ungar, Andrea
AU - Prati, Patrizio
AU - Di Serio, Claudia
AU - Geppetti, Pierangelo
AU - Masotti, Giulio
AU - Serneri, Gian Gastone Neri
AU - Gensini, Gian Franco
PY - 2006/12
Y1 - 2006/12
N2 - The aim of this study was to investigate the cerebrovascular adaptability to 2 sequential pressor stimuli in elderly patients with isolated systolic hypertension. Ten healthy elderly normotensive subjects (68 to 82 years), 10 elderly subjects with isolated systolic hypertension (63 to 82 years), and 10 young normotensive subjects (24 to 40 years) took part in the study. A pressor reaction, using sequential cold pressor and handgrip stimulation, was induced. The cerebrovascular response to the pressor stimulation was measured by transcranial Doppler determination of the mean flow velocity in the middle cerebral arteries. In all of the subjects, blood pressure increased during handgrip (+12 mm Hg, P
AB - The aim of this study was to investigate the cerebrovascular adaptability to 2 sequential pressor stimuli in elderly patients with isolated systolic hypertension. Ten healthy elderly normotensive subjects (68 to 82 years), 10 elderly subjects with isolated systolic hypertension (63 to 82 years), and 10 young normotensive subjects (24 to 40 years) took part in the study. A pressor reaction, using sequential cold pressor and handgrip stimulation, was induced. The cerebrovascular response to the pressor stimulation was measured by transcranial Doppler determination of the mean flow velocity in the middle cerebral arteries. In all of the subjects, blood pressure increased during handgrip (+12 mm Hg, P
KW - Adrenergic stimulation
KW - Cerebrovascular adaptability
KW - Isolated systolic hypertension
UR - http://www.scopus.com/inward/record.url?scp=33751071600&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33751071600&partnerID=8YFLogxK
U2 - 10.1161/01.HYP.0000248533.58693.c4
DO - 10.1161/01.HYP.0000248533.58693.c4
M3 - Article
C2 - 17060510
AN - SCOPUS:33751071600
VL - 48
SP - 1143
EP - 1150
JO - Hypertension
JF - Hypertension
SN - 0194-911X
IS - 6
ER -