Abnormal tactile temporal discrimination in psychogenic dystonia

F. Morgante, M. Tinazzi, G. Squintani, D. Martino, G. Defazio, L. Romito, A. Albanese, A. Di Matteo, A. Quartarone, P. Girlanda, M. Fiorio, A. Berardelli

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Objective: Neurophysiologic studies demonstrated that patients with primary torsion dystonia (PTD) and with psychogenic dystonia (Psy-D) share similar abnormalities in the motor system. In this study, we evaluated somatosensory function in Psy-D by testing temporal discrimination threshold (TDT), and compared the results with those obtained in patients with PTD. Methods: TDT of tactile stimuli was assessed in 10 patients with Psy-D, 10 patients with PTD, and 16 control subjects. The 2 groups of patients were matched for age, gender, disease duration, and distribution of dystonia. Tactile stimuli consisted of pairs of non-noxious electrical shocks delivered to the right or left hand at interstimulus interval increasing from 0 to 400 msec, in 10-msec steps. TDT was defined as the value at which subjects recognized the 2 stimuli as asynchronous. Results: TDT was higher in Psy-D and PTD compared to control subjects, for both the right and the left hand. In a subgroup of patients with unilateral dystonia (Psy-D = 4, PTD = 5), TDT did not differ between the affected and the unaffected side in both groups of patients. Disease duration was not correlated to the increased TDT value. Conclusions: Our study suggests an impaired processing of somatosensory inputs in both Psy-D and PTD. These abnormalities might represent a neurophysiological trait predisposing to develop a dystonic posture triggered by psychiatric and psychological factors.

Original languageEnglish
Pages (from-to)1191-1197
Number of pages7
JournalNeurology
Volume77
Issue number12
DOIs
Publication statusPublished - Sep 20 2011

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Dystonic Disorders
Touch
Dystonia
Hand
Discrimination
Posture
Psychiatry
Dystonia musculorum deformans type 1
Shock
Psychology

ASJC Scopus subject areas

  • Clinical Neurology
  • Arts and Humanities (miscellaneous)

Cite this

Abnormal tactile temporal discrimination in psychogenic dystonia. / Morgante, F.; Tinazzi, M.; Squintani, G.; Martino, D.; Defazio, G.; Romito, L.; Albanese, A.; Di Matteo, A.; Quartarone, A.; Girlanda, P.; Fiorio, M.; Berardelli, A.

In: Neurology, Vol. 77, No. 12, 20.09.2011, p. 1191-1197.

Research output: Contribution to journalArticle

Morgante, F, Tinazzi, M, Squintani, G, Martino, D, Defazio, G, Romito, L, Albanese, A, Di Matteo, A, Quartarone, A, Girlanda, P, Fiorio, M & Berardelli, A 2011, 'Abnormal tactile temporal discrimination in psychogenic dystonia', Neurology, vol. 77, no. 12, pp. 1191-1197. https://doi.org/10.1212/WNL.0b013e31822f0449
Morgante F, Tinazzi M, Squintani G, Martino D, Defazio G, Romito L et al. Abnormal tactile temporal discrimination in psychogenic dystonia. Neurology. 2011 Sep 20;77(12):1191-1197. https://doi.org/10.1212/WNL.0b013e31822f0449
Morgante, F. ; Tinazzi, M. ; Squintani, G. ; Martino, D. ; Defazio, G. ; Romito, L. ; Albanese, A. ; Di Matteo, A. ; Quartarone, A. ; Girlanda, P. ; Fiorio, M. ; Berardelli, A. / Abnormal tactile temporal discrimination in psychogenic dystonia. In: Neurology. 2011 ; Vol. 77, No. 12. pp. 1191-1197.
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