Abnormalities of central motor conduction in asymptomatic HIV-positive patients. Significance and prognostic value.

C. Zandrini; C. Ciano; E. Alfonsi; G. Sandrini; L. Minoli; A. Moglia

Abnormalities of central motor conduction in asymptomatic HIV-positive patients. Significance and prognostic value.

C. Zandrini, C. Ciano, E. Alfonsi, G. Sandrini, L. Minoli, A. Moglia

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Abstract

Percutaneous magnetic stimulation of the brain and spinal cord is a technique developed to demonstrate early and subclinical abnormalities in corticomotoneuron pathways. Central motor conduction time (CMCT) was evaluated in 58 HIV-seropositive patients neurologically asymptomatic (CDC groups II and III) and in two control groups. CMCT was abnormal in about 50% of HIV-seropositive patients. These electrophysiological abnormalities seem to have a negative prognostic value since about 64% of the patients with abnormal parameters seem to progress more rapidly to AIDS stages.

Original language	English
Pages (from-to)	296-300
Number of pages	5
Journal	Acta Neurologica
Volume	12
Issue number	4
Publication status	Published - Aug 1990

ASJC Scopus subject areas

Clinical Neurology

Cite this

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abstract = "Percutaneous magnetic stimulation of the brain and spinal cord is a technique developed to demonstrate early and subclinical abnormalities in corticomotoneuron pathways. Central motor conduction time (CMCT) was evaluated in 58 HIV-seropositive patients neurologically asymptomatic (CDC groups II and III) and in two control groups. CMCT was abnormal in about 50% of HIV-seropositive patients. These electrophysiological abnormalities seem to have a negative prognostic value since about 64% of the patients with abnormal parameters seem to progress more rapidly to AIDS stages.",

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AU - Zandrini, C.

AU - Ciano, C.

AU - Alfonsi, E.

AU - Sandrini, G.

AU - Minoli, L.

AU - Moglia, A.

PY - 1990/8

Y1 - 1990/8

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AB - Percutaneous magnetic stimulation of the brain and spinal cord is a technique developed to demonstrate early and subclinical abnormalities in corticomotoneuron pathways. Central motor conduction time (CMCT) was evaluated in 58 HIV-seropositive patients neurologically asymptomatic (CDC groups II and III) and in two control groups. CMCT was abnormal in about 50% of HIV-seropositive patients. These electrophysiological abnormalities seem to have a negative prognostic value since about 64% of the patients with abnormal parameters seem to progress more rapidly to AIDS stages.

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JF - Acta Neurologica

SN - 0001-6276

IS - 4

ER -

Abnormalities of central motor conduction in asymptomatic HIV-positive patients. Significance and prognostic value.

Abstract

ASJC Scopus subject areas

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