Abnormalities of central motor conduction in asymptomatic HIV-positive patients. Significance and prognostic value.

C. Zandrini, C. Ciano, E. Alfonsi, G. Sandrini, L. Minoli, A. Moglia

Research output: Contribution to journalArticle

Abstract

Percutaneous magnetic stimulation of the brain and spinal cord is a technique developed to demonstrate early and subclinical abnormalities in corticomotoneuron pathways. Central motor conduction time (CMCT) was evaluated in 58 HIV-seropositive patients neurologically asymptomatic (CDC groups II and III) and in two control groups. CMCT was abnormal in about 50% of HIV-seropositive patients. These electrophysiological abnormalities seem to have a negative prognostic value since about 64% of the patients with abnormal parameters seem to progress more rapidly to AIDS stages.

Original languageEnglish
Pages (from-to)296-300
Number of pages5
JournalActa Neurologica
Volume12
Issue number4
Publication statusPublished - Aug 1990

ASJC Scopus subject areas

  • Clinical Neurology

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