Absence of water at the sixth co-ordination site in ferric Aplysia myoglobin

Giorgio M. Giacometti, Paolo Ascenzi, Maurizio Brunori, Giorgio Rigatti, Giovanni Giacometti, Martino Bolognesi

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

The acidic ferric form of hemoglobin and myoglobin carries a water molecule as the sixth ligand of the iron atom. On the other hand, Aplysia met myoglobin shows a pentaco-ordinated active site below the pK of the acid-alkaline transition (7.5). This finding rationalizes some peculiar properties of Aplysia myoglobin as compared with sperm whale myoglobin.

Original languageEnglish
Pages (from-to)315-319
Number of pages5
JournalJournal of Molecular Biology
Volume151
Issue number2
DOIs
Publication statusPublished - Sep 15 1981

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Aplysia
Myoglobin
Water
Sperm Whale
Metmyoglobin
Catalytic Domain
Hemoglobins
Iron
Ligands
Acids

ASJC Scopus subject areas

  • Virology

Cite this

Giacometti, G. M., Ascenzi, P., Brunori, M., Rigatti, G., Giacometti, G., & Bolognesi, M. (1981). Absence of water at the sixth co-ordination site in ferric Aplysia myoglobin. Journal of Molecular Biology, 151(2), 315-319. https://doi.org/10.1016/0022-2836(81)90518-0

Absence of water at the sixth co-ordination site in ferric Aplysia myoglobin. / Giacometti, Giorgio M.; Ascenzi, Paolo; Brunori, Maurizio; Rigatti, Giorgio; Giacometti, Giovanni; Bolognesi, Martino.

In: Journal of Molecular Biology, Vol. 151, No. 2, 15.09.1981, p. 315-319.

Research output: Contribution to journalArticle

Giacometti, GM, Ascenzi, P, Brunori, M, Rigatti, G, Giacometti, G & Bolognesi, M 1981, 'Absence of water at the sixth co-ordination site in ferric Aplysia myoglobin', Journal of Molecular Biology, vol. 151, no. 2, pp. 315-319. https://doi.org/10.1016/0022-2836(81)90518-0
Giacometti GM, Ascenzi P, Brunori M, Rigatti G, Giacometti G, Bolognesi M. Absence of water at the sixth co-ordination site in ferric Aplysia myoglobin. Journal of Molecular Biology. 1981 Sep 15;151(2):315-319. https://doi.org/10.1016/0022-2836(81)90518-0
Giacometti, Giorgio M. ; Ascenzi, Paolo ; Brunori, Maurizio ; Rigatti, Giorgio ; Giacometti, Giovanni ; Bolognesi, Martino. / Absence of water at the sixth co-ordination site in ferric Aplysia myoglobin. In: Journal of Molecular Biology. 1981 ; Vol. 151, No. 2. pp. 315-319.
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