Translated title of the contribution: Acantholytic dyskeratotic epidermal naevus. Clinical case

F. Zorzi, A. Coggi

Research output: Contribution to journalArticlepeer-review


The exact nosography of cases described in the literature as 'acantholytic dyskeratotic epidermal naevus' (ADEN) or zosteriform unilateral follicular keratosis is a hardy debated topic. Clinical case. A 45 year-old man with familial anamnesis negative for dermatological diseases was evaluated for follicular and extrafollicular brownish gray keratotic; papules located along Blaschko lines on the right side of his chest. These lesions worsen during summertime. The histopathological examination showed a pattern indistinguishable from Darier's disease (DD), with typical focal acantholitic dyskeratosis. Discussion. Males and females are equally affected with this disease that begins in half the cases in middle age. Every part of the body can be involved. The lesions begin and worsen preferentially during summertime. The distribution may be linear, zosteriform or following Blaschko lines. Cases with bilateral distribution and mucosal, annessial and omolateral palmoplantar involvement have been reported. Both naevoid and localized DD origin have been hypothesized. Even if the matter is still debated we think that our case could be diagnosed as ADEN.

Translated title of the contributionAcantholytic dyskeratotic epidermal naevus. Clinical case
Original languageItalian
Pages (from-to)393-396
Number of pages4
JournalGiornale Italiano di Dermatologia e Venereologia
Issue number6
Publication statusPublished - 1995

ASJC Scopus subject areas

  • Dermatology


Dive into the research topics of 'Acantholytic dyskeratotic epidermal naevus. Clinical case'. Together they form a unique fingerprint.

Cite this