Accelerated hypo-fractionation by biological equivalent DVH for patients affected by gastric carcinoma in postoperative concomitant radiochemotherapy

P. Pedicini; M. Mazziotta; S. Clemente; M. Cozzolino; L. Caporaso; P. Sanpaolo; V. Barbieri; L. Lapadula; G. Castaldo; V. Fusco

doi:10.1007/978-3-642-03902-7-63

Accelerated hypo-fractionation by biological equivalent DVH for patients affected by gastric carcinoma in postoperative concomitant radiochemotherapy

P. Pedicini, M. Mazziotta, S. Clemente, M. Cozzolino, L. Caporaso, P. Sanpaolo, V. Barbieri, L. Lapadula, G. Castaldo, V. Fusco

IRCCS Centro di Riferimento Oncologico della Basilicata (CROB)

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Recent result of clinical trial on carcinoma of stomach demonstrate an advantage to adjuvant postoperative chemo-radiotherapy witch is now used more commonly for gastric cancer. However remain some doubt for toxicity as for the optimal chemotherapy regimen as for the optimal method of radiation delivery. To increase the biological effectiveness and, at same time, to reduce toxicity of conventional radiotherapy we tested many alternative fractionation schemes of dose radiation, using a biological equivalent Histogram Dose Volume (DVH) for prior analysis and as tool for the assessment and choice of fractionation dose biologically more effective.

Original language	English
Title of host publication	IFMBE Proceedings
Pages	223-226
Number of pages	4
Volume	25
Edition	3
DOIs	https://doi.org/10.1007/978-3-642-03902-7-63
Publication status	Published - 2009
Event	World Congress on Medical Physics and Biomedical Engineering: Radiation Protection and Dosimetry, Biological Effects of Radiation - Munich, Germany Duration: Sep 7 2009 → Sep 12 2009

Other

Other	World Congress on Medical Physics and Biomedical Engineering: Radiation Protection and Dosimetry, Biological Effects of Radiation
Country	Germany
City	Munich
Period	9/7/09 → 9/12/09

Keywords

Biological equivalent dose
Chemo-radiotherapy
Dose volume histogram
Fractionation
Tolerance dose

ASJC Scopus subject areas

Biomedical Engineering
Bioengineering

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Pedicini, P., Mazziotta, M., Clemente, S., Cozzolino, M., Caporaso, L., Sanpaolo, P., Barbieri, V., Lapadula, L., Castaldo, G., & Fusco, V. (2009). Accelerated hypo-fractionation by biological equivalent DVH for patients affected by gastric carcinoma in postoperative concomitant radiochemotherapy. In IFMBE Proceedings (3 ed., Vol. 25, pp. 223-226) https://doi.org/10.1007/978-3-642-03902-7-63

Accelerated hypo-fractionation by biological equivalent DVH for patients affected by gastric carcinoma in postoperative concomitant radiochemotherapy. / Pedicini, P.; Mazziotta, M.; Clemente, S.; Cozzolino, M.; Caporaso, L.; Sanpaolo, P.; Barbieri, V.; Lapadula, L.; Castaldo, G.; Fusco, V.

IFMBE Proceedings. Vol. 25 3. ed. 2009. p. 223-226.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Pedicini, P, Mazziotta, M, Clemente, S, Cozzolino, M, Caporaso, L, Sanpaolo, P, Barbieri, V, Lapadula, L, Castaldo, G & Fusco, V 2009, Accelerated hypo-fractionation by biological equivalent DVH for patients affected by gastric carcinoma in postoperative concomitant radiochemotherapy. in IFMBE Proceedings. 3 edn, vol. 25, pp. 223-226, World Congress on Medical Physics and Biomedical Engineering: Radiation Protection and Dosimetry, Biological Effects of Radiation, Munich, Germany, 9/7/09. https://doi.org/10.1007/978-3-642-03902-7-63

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abstract = "Recent result of clinical trial on carcinoma of stomach demonstrate an advantage to adjuvant postoperative chemo-radiotherapy witch is now used more commonly for gastric cancer. However remain some doubt for toxicity as for the optimal chemotherapy regimen as for the optimal method of radiation delivery. To increase the biological effectiveness and, at same time, to reduce toxicity of conventional radiotherapy we tested many alternative fractionation schemes of dose radiation, using a biological equivalent Histogram Dose Volume (DVH) for prior analysis and as tool for the assessment and choice of fractionation dose biologically more effective.",

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AU - Pedicini, P.

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AU - Cozzolino, M.

AU - Caporaso, L.

AU - Sanpaolo, P.

AU - Barbieri, V.

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Accelerated hypo-fractionation by biological equivalent DVH for patients affected by gastric carcinoma in postoperative concomitant radiochemotherapy

Abstract

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Keywords

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