Accelerated partial breast irradiation in early breast cancer: Focus on intraoperative treatment with electrons (ELIOT)

Stefano Zurrida, Maria Cristina Leonardi, Andrés Del Castillo, Roberta Lazzari, Paolo Arnone, Piero Caldarella

Research output: Contribution to journalArticle

Abstract

Wide tumor resection plus postoperative whole breast irradiation is standard treatment for early breast cancer. Irradiation decreases recurrence rates, but may cause poor cosmesis, breast pain, and cardiac and lung toxicity. Accelerated partial breast irradiation is increasingly used in the hope of increasing convenience, decreasing sequelae and maintaining cure rates. Intraoperative radiotherapy with electrons is an attractive accelerated partial breast irradiation technique because collimator placement is under the direct control of the surgeon who removes the tumor, the skin is spared, shielding protects the chest wall and complete irradiation can be given in a single intraoperative session (avoiding 5-7 weeks of whole breast irradiation). Intraoperative radiotherapy with electrons seems as safe as whole breast irradiation; however, long-term results on local control and survival are not available yet.

Original languageEnglish
Pages (from-to)89-98
Number of pages10
JournalWomen's Health
Volume8
Issue number1
DOIs
Publication statusPublished - Jan 2012

Keywords

  • accelerated partial breast irradiation
  • early breast cancer
  • intraoperative radiotherapy
  • intraoperative radiotherapy with electrons

ASJC Scopus subject areas

  • Medicine(all)

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