Accessory cell function in asymptomatic human immunodeficiency virus-infected patients

M. Clerici, N. I. Stocks, R. A. Zajac, R. N. Boswell, G. M. Shearer

Research output: Contribution to journalArticle

Abstract

Peripheral blood mononuclear cells from human immunodeficiency virus seropositive (HIV+) individuals who did not exhibit symptoms of acquired immunodeficiency syndrome (AIDS) (Walter Reed Stage 1 patients) were tested for accessory cell function for presentation of recall antigens to autologous T lymphocytes and for presentation of HLA alloantigens to T lymphocytes from healthy, HIV- donors. Neither experimental model indicated a defect in accessory cell function at this early stage after HIV infection, although our study does not exclude the possibility of accessory cell dysfunction at a later stage of AIDS development.

Original languageEnglish
Pages (from-to)168-173
Number of pages6
JournalClinical Immunology and Immunopathology
Volume54
Issue number2
DOIs
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy
  • Pathology and Forensic Medicine

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