Accumulation and metabolism of uneven fatty acids present in single cell protein

A. Bizzi, E. Veneroni, M. T. Tacconi, A. M. Codegoni, R. Pagani, M. Cini, S. Garattini

Research output: Contribution to journalArticle

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Abstract

Liquipron and Toprina, obtained by growing yeasts (Candida maltosa and Candida lipolytica) on n-hydrocarbons, were investigated to ascertain the biological significance and possible toxicological implications of their high content of uneven fatty acids (UFA). It was confirmed that the extent to which UFA accumulate in adipose tissue of rats fed the 2 products reflects only partially their UFA contents. The presence of UFA in rat tissues does not appear to alter intermediate metabolism. The capacity of liver mitochondria to oxidize palmitic acid was similar in control and in Liquipron-treated rats. Palmitic acid and heptadecanoic acid did not compete for oxidation when mixed at concentrations which reflect their presence in the tissues of animals fed high levels of Liquipron.

Original languageEnglish
Pages (from-to)227-240
Number of pages14
JournalToxicology Letters
Volume5
Issue number3-4
DOIs
Publication statusPublished - 1980

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Metabolism
Fatty Acids
Rats
Palmitic Acid
Candida
Tissue
Mitochondria
Liver Mitochondrion
Hydrocarbons
Liver
Yeast
Toxicology
Adipose Tissue
Animals
Yeasts
Oxidation
single cell proteins

ASJC Scopus subject areas

  • Toxicology

Cite this

Bizzi, A., Veneroni, E., Tacconi, M. T., Codegoni, A. M., Pagani, R., Cini, M., & Garattini, S. (1980). Accumulation and metabolism of uneven fatty acids present in single cell protein. Toxicology Letters, 5(3-4), 227-240. https://doi.org/10.1016/0378-4274(80)90065-X

Accumulation and metabolism of uneven fatty acids present in single cell protein. / Bizzi, A.; Veneroni, E.; Tacconi, M. T.; Codegoni, A. M.; Pagani, R.; Cini, M.; Garattini, S.

In: Toxicology Letters, Vol. 5, No. 3-4, 1980, p. 227-240.

Research output: Contribution to journalArticle

Bizzi, A, Veneroni, E, Tacconi, MT, Codegoni, AM, Pagani, R, Cini, M & Garattini, S 1980, 'Accumulation and metabolism of uneven fatty acids present in single cell protein', Toxicology Letters, vol. 5, no. 3-4, pp. 227-240. https://doi.org/10.1016/0378-4274(80)90065-X
Bizzi A, Veneroni E, Tacconi MT, Codegoni AM, Pagani R, Cini M et al. Accumulation and metabolism of uneven fatty acids present in single cell protein. Toxicology Letters. 1980;5(3-4):227-240. https://doi.org/10.1016/0378-4274(80)90065-X
Bizzi, A. ; Veneroni, E. ; Tacconi, M. T. ; Codegoni, A. M. ; Pagani, R. ; Cini, M. ; Garattini, S. / Accumulation and metabolism of uneven fatty acids present in single cell protein. In: Toxicology Letters. 1980 ; Vol. 5, No. 3-4. pp. 227-240.
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