Abstract
Transient elastography (TE) has received increasing attention as a means to evaluate disease progression in chronic liver disease patients. In this study, we assessed the value of TE for the prediction of fibrosis stage in a cohort of pediatric patients with nonalcoholic steatohepatitis. Furthermore, TE interobserver agreement was evaluated. TE was performed in 52 consecutive biopsy-proven nonalcoholic steatohepatitis patients (32 males, 20 females, age 13.6 ± 2.44 years). The area under the receiver operating characteristic curves for the prediction of "any" (≥1), significant (≥2), or advanced fibrosis (≥3) were 0.977, 0.992, and 1, respectively. Calculation of multilevel likelihood ratios showed that TE values
| Original language | English |
|---|---|
| Pages (from-to) | 442-448 |
| Number of pages | 7 |
| Journal | Hepatology |
| Volume | 48 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Aug 2008 |
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ASJC Scopus subject areas
- Hepatology
Cite this
Accuracy and reproducibility of transient elastography for the diagnosis of fibrosis in pediatric nonalcoholic steatohepatitis. / Nobili, Valerio; Vizzutti, Francesco; Arena, Umberto; Abraldes, Juan G.; Marra, Fabio; Pietrobattista, Andrea; Fruhwirth, Rodolfo; Marcellini, Matilde; Pinzani, Massimo.
In: Hepatology, Vol. 48, No. 2, 08.2008, p. 442-448.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Accuracy and reproducibility of transient elastography for the diagnosis of fibrosis in pediatric nonalcoholic steatohepatitis
AU - Nobili, Valerio
AU - Vizzutti, Francesco
AU - Arena, Umberto
AU - Abraldes, Juan G.
AU - Marra, Fabio
AU - Pietrobattista, Andrea
AU - Fruhwirth, Rodolfo
AU - Marcellini, Matilde
AU - Pinzani, Massimo
PY - 2008/8
Y1 - 2008/8
N2 - Transient elastography (TE) has received increasing attention as a means to evaluate disease progression in chronic liver disease patients. In this study, we assessed the value of TE for the prediction of fibrosis stage in a cohort of pediatric patients with nonalcoholic steatohepatitis. Furthermore, TE interobserver agreement was evaluated. TE was performed in 52 consecutive biopsy-proven nonalcoholic steatohepatitis patients (32 males, 20 females, age 13.6 ± 2.44 years). The area under the receiver operating characteristic curves for the prediction of "any" (≥1), significant (≥2), or advanced fibrosis (≥3) were 0.977, 0.992, and 1, respectively. Calculation of multilevel likelihood ratios showed that TE values
AB - Transient elastography (TE) has received increasing attention as a means to evaluate disease progression in chronic liver disease patients. In this study, we assessed the value of TE for the prediction of fibrosis stage in a cohort of pediatric patients with nonalcoholic steatohepatitis. Furthermore, TE interobserver agreement was evaluated. TE was performed in 52 consecutive biopsy-proven nonalcoholic steatohepatitis patients (32 males, 20 females, age 13.6 ± 2.44 years). The area under the receiver operating characteristic curves for the prediction of "any" (≥1), significant (≥2), or advanced fibrosis (≥3) were 0.977, 0.992, and 1, respectively. Calculation of multilevel likelihood ratios showed that TE values
UR - http://www.scopus.com/inward/record.url?scp=49649105500&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=49649105500&partnerID=8YFLogxK
U2 - 10.1002/hep.22376
DO - 10.1002/hep.22376
M3 - Article
VL - 48
SP - 442
EP - 448
JO - Hepatology
JF - Hepatology
SN - 0270-9139
IS - 2
ER -