TY - JOUR
T1 - Accuracy and reproducibility of transient elastography for the diagnosis of fibrosis in pediatric nonalcoholic steatohepatitis
AU - Nobili, Valerio
AU - Vizzutti, Francesco
AU - Arena, Umberto
AU - Abraldes, Juan G.
AU - Marra, Fabio
AU - Pietrobattista, Andrea
AU - Fruhwirth, Rodolfo
AU - Marcellini, Matilde
AU - Pinzani, Massimo
PY - 2008/8
Y1 - 2008/8
N2 - Transient elastography (TE) has received increasing attention as a means to evaluate disease progression in chronic liver disease patients. In this study, we assessed the value of TE for the prediction of fibrosis stage in a cohort of pediatric patients with nonalcoholic steatohepatitis. Furthermore, TE interobserver agreement was evaluated. TE was performed in 52 consecutive biopsy-proven nonalcoholic steatohepatitis patients (32 males, 20 females, age 13.6 ± 2.44 years). The area under the receiver operating characteristic curves for the prediction of "any" (≥1), significant (≥2), or advanced fibrosis (≥3) were 0.977, 0.992, and 1, respectively. Calculation of multilevel likelihood ratios showed that TE values
AB - Transient elastography (TE) has received increasing attention as a means to evaluate disease progression in chronic liver disease patients. In this study, we assessed the value of TE for the prediction of fibrosis stage in a cohort of pediatric patients with nonalcoholic steatohepatitis. Furthermore, TE interobserver agreement was evaluated. TE was performed in 52 consecutive biopsy-proven nonalcoholic steatohepatitis patients (32 males, 20 females, age 13.6 ± 2.44 years). The area under the receiver operating characteristic curves for the prediction of "any" (≥1), significant (≥2), or advanced fibrosis (≥3) were 0.977, 0.992, and 1, respectively. Calculation of multilevel likelihood ratios showed that TE values
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U2 - 10.1002/hep.22376
DO - 10.1002/hep.22376
M3 - Article
C2 - 18563842
AN - SCOPUS:49649105500
VL - 48
SP - 442
EP - 448
JO - Hepatology
JF - Hepatology
SN - 0270-9139
IS - 2
ER -