Accuracy of Doppler technique in estimating acute changes of right heart chamber pressures in pulmonary hypertension

M. Pepi, P. Sganzerla, P. Moruzzi, C. Fiorentini, M. D. Guazzi

Research output: Contribution to journalArticlepeer-review

Abstract

In 9 patients with pulmonary hypertension secondary to pulmonary, mitral valve, or primary myocardial diseases, we compared the Doppler-derived right ventricular-right atrial gradient (RV-RA Grad) with the transtricuspid gradient recorded simultaneously through right heart catheterization. We confirmed that Doppler estimation of the transtricuspid gradient is accurate in stable hemodynamic conditions. We also proved that the accuracy is maintained when the right ventricular filling is changed acutely, such as obtained with distention of a rubber balloon in the inferior vena cava. Moreover, the two formulas currently used to derive right ventricular systolic pressure (Doppler RV-RA Grad + 10 mmHg; Doppler RV-RA Grad x 1.1 + 14 mmHg) from Doppler transtricuspid gradient proved to be correct both during steady state and when venous return was altered acutely. This observation validates the Doppler method as a reliable estimator (in the absence of impedance to right ventricular outflow) of the systolic pulmonary pressure, not only in the baseline but also during interventions that may alter acutely the venous return and filling of the right heart.

Original languageEnglish
Pages (from-to)53-58
Number of pages6
JournalJournal of Cardiovascular Technology
Volume8
Issue number1
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Cardiology and Cardiovascular Medicine

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