Acetylcholinesterase activity in rat thymus after immunostimulation with interleukin β

Daniela Cavallotti, Marco Artico, Carlo Cavallotti, Giandomenico Iannetti, Alessandro Frati

Research output: Contribution to journalArticle

Abstract

The occurrence and distribution of Acetylcholinesterase (AChE) activity were examined in the thymus of normal and immune-stimulated adult and aged rats using biochemical and enzymhistochemical methods. Specific AChE reactivity was found primarily in the arteries and, to a lesser extent, in the veins. Only a small amount of activity could be observed in association with the subcapsular and medullary part of the parenchyma and nerve fibers. Our findings indicate that AChE activity in the rat thymus increases after treatment with interleukin β. In fact treatment with interleukin β induces an increase of protein content, of the amounts of AChE biochemically assayed and at the levels of AChE histoenzymatically stained. Furthermore, staining of the different structures of the thymus in treated or untreated rats shows that the significant modifications concern the parenchyma, the structures resembling nerve fibers and the whole thymus, while only small changes are observed in AChE activity located in the walls of arteries, veins and lymphatic vessels.

Original languageEnglish
Pages (from-to)243-248
Number of pages6
JournalAnnals of Anatomy
Volume182
Issue number3
Publication statusPublished - 2000

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Keywords

  • AchE
  • Immunostimulation
  • Interleukin β
  • Thymus

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Anatomy

Cite this

Cavallotti, D., Artico, M., Cavallotti, C., Iannetti, G., & Frati, A. (2000). Acetylcholinesterase activity in rat thymus after immunostimulation with interleukin β. Annals of Anatomy, 182(3), 243-248.