Achalasia results from irreversible alterations of the esophageal myenteric plexus. The target of treatment in this setting is to reduce lower esophageal sphincter resistance to passage of the bolus. Definitive treatment of the disease requires pneumatic dilation or Heller myotomy. Although no controlled studies comparing modern endoscopic and surgical techniques are available, laparoscopic surgery is emerging as the initial intervention of choice.
|Number of pages||3|
|Journal||Canadian Journal of Gastroenterology|
|Publication status||Published - May 2000|
- Botulinum toxin
- Lower esophageal sphincter
- Pneumatic dilation
ASJC Scopus subject areas