ACh/Dopamine Crosstalk in Motor Control and Reward: A Crucial Role for α6-Containing Nicotinic Receptors?

Paolo Calabresi, Massimiliano Di Filippo

Research output: Contribution to journalArticlepeer-review

Abstract

The midbrain dopaminergic system is a key element in the control of motor activity, cognition, and the motivational effects of drugs of abuse, including nicotine. In this issue of Neuron, Drenan et al. find that α6-containing nicotinic acetylcholine receptors might selectively activate mesolimbic and mesostriatal dopaminergic neurons, enhancing striatal dopamine release and its behavioral consequences.

Original languageEnglish
Pages (from-to)4-7
Number of pages4
JournalNeuron
Volume60
Issue number1
DOIs
Publication statusPublished - Oct 9 2008

ASJC Scopus subject areas

  • Neuroscience(all)

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