ACh/Dopamine Crosstalk in Motor Control and Reward

A Crucial Role for α6-Containing Nicotinic Receptors?

Paolo Calabresi, Massimiliano Di Filippo

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The midbrain dopaminergic system is a key element in the control of motor activity, cognition, and the motivational effects of drugs of abuse, including nicotine. In this issue of Neuron, Drenan et al. find that α6-containing nicotinic acetylcholine receptors might selectively activate mesolimbic and mesostriatal dopaminergic neurons, enhancing striatal dopamine release and its behavioral consequences.

Original languageEnglish
Pages (from-to)4-7
Number of pages4
JournalNeuron
Volume60
Issue number1
DOIs
Publication statusPublished - Oct 9 2008

Fingerprint

Corpus Striatum
Dopaminergic Neurons
Nicotinic Receptors
Street Drugs
Mesencephalon
Nicotine
Reward
Cognition
Dopamine
Motor Activity
Neurons

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

ACh/Dopamine Crosstalk in Motor Control and Reward : A Crucial Role for α6-Containing Nicotinic Receptors? / Calabresi, Paolo; Di Filippo, Massimiliano.

In: Neuron, Vol. 60, No. 1, 09.10.2008, p. 4-7.

Research output: Contribution to journalArticle

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