Acidified glycerol lysis test

A screening test for spherocytosis

A. Zanella, C. Izzo, P. Rebulla, F. Zanuso, L. Perroni, G. Sirchia

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

Acidified glycerol lysis test (AGLT) is a screening procedure which has been developed for spherocytosis AGLT was found positive in 100% of 48 patients suffering from hereditary spherocytosis, 100% of nine couples of affected parents, and 86% of 14 couples of clinically healthy parents. The test was positive in acquired spherocytosis and negative in normal controls. AGLT appears to have a predictive value higher than the entire battery of conventional tests. It is simple, rapid, inexpensive, gives clear-cut results and requires minute amounts of blood. It can be performed on blood stored for up to 24 h.

Original languageEnglish
Pages (from-to)481-486
Number of pages6
JournalBritish Journal of Haematology
Volume45
Issue number3
Publication statusPublished - 1980

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Glycerol
Parents
Hereditary Spherocytosis

ASJC Scopus subject areas

  • Hematology

Cite this

Zanella, A., Izzo, C., Rebulla, P., Zanuso, F., Perroni, L., & Sirchia, G. (1980). Acidified glycerol lysis test: A screening test for spherocytosis. British Journal of Haematology, 45(3), 481-486.

Acidified glycerol lysis test : A screening test for spherocytosis. / Zanella, A.; Izzo, C.; Rebulla, P.; Zanuso, F.; Perroni, L.; Sirchia, G.

In: British Journal of Haematology, Vol. 45, No. 3, 1980, p. 481-486.

Research output: Contribution to journalArticle

Zanella, A, Izzo, C, Rebulla, P, Zanuso, F, Perroni, L & Sirchia, G 1980, 'Acidified glycerol lysis test: A screening test for spherocytosis', British Journal of Haematology, vol. 45, no. 3, pp. 481-486.
Zanella A, Izzo C, Rebulla P, Zanuso F, Perroni L, Sirchia G. Acidified glycerol lysis test: A screening test for spherocytosis. British Journal of Haematology. 1980;45(3):481-486.
Zanella, A. ; Izzo, C. ; Rebulla, P. ; Zanuso, F. ; Perroni, L. ; Sirchia, G. / Acidified glycerol lysis test : A screening test for spherocytosis. In: British Journal of Haematology. 1980 ; Vol. 45, No. 3. pp. 481-486.
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