Acoustic radiation force impulse of the liver

Mirko D'Onofrio, Stefano Crosara, Riccardo de Robertis, Stefano Canestrini, Emanuele Demozzi, Anna Gallotti, Roberto Pozzi Mucelli

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Acoustic radiation force impulse (ARFI) imaging is a new and promising ultrasound-based diagnostic technique that, evaluating the wave propagation speed, allows the assessment of the tissue stiffness. ARFI is implemented in the ultrasound scanner. By short-duration acoustic radiation forces (less than 1 ms), localized displacements are generated in a selected region of interest not requiring any external compression so reducing the operator dependency. The generated wave scan provides qualitative or quantitative (wave velocity values) responses. Several non-invasive methods for assessing the staging of fibrosis are used, in order to avoid liver biopsy. Liver function tests and transient elastography are non-invasive, sensitive and accurate tools for the assessment of liver fibrosis and for the discrimination between cirrhotic and non-cirrhotic liver. Many published studies analyse ARFI performance and feasibility in studying diffuse liver diseases and compare them to other diagnostic imaging modalities such as conventional ultrasonography and transient elastography. Solid focal liver lesions, both benign and malignant, are common findings during abdominal examinations. The accurate characterization and differential diagnosis are important aims of all the imaging modalities available today. Only few papers describe the application of ARFI technology in the study of solid focal liver lesions, with different results. In the present study, the existing literature, to the best of our knowledge, about ARFI application on diffuse and focal liver pathology has been evaluated and results and statistical analyses have been compared, bringing to the conclusion that ARFI can be used in the study of the liver with similar accuracy as transient elastography in diagnosing significant fibrosis or cirrhosis and has got some advantages in respect to transient elastography since it does not require separate equipment, better displays anatomical structures and measurements can be successfully carried out almost in every patient.

Original languageEnglish
Pages (from-to)4841-4849
Number of pages9
JournalWorld Journal of Gastroenterology
Volume19
Issue number30
DOIs
Publication statusPublished - 2013

Fingerprint

Elasticity Imaging Techniques
Acoustics
Radiation
Liver
Fibrosis
Ultrasonography
Liver Function Tests
Diagnostic Imaging
Liver Cirrhosis
Liver Diseases
Differential Diagnosis
Pathology
Technology
Biopsy
Equipment and Supplies

Keywords

  • Acoustic radiation force impulse imaging
  • Diffuse liver pathology
  • Focal liver lesion
  • Sonoelastography

ASJC Scopus subject areas

  • Gastroenterology

Cite this

D'Onofrio, M., Crosara, S., de Robertis, R., Canestrini, S., Demozzi, E., Gallotti, A., & Pozzi Mucelli, R. (2013). Acoustic radiation force impulse of the liver. World Journal of Gastroenterology, 19(30), 4841-4849. https://doi.org/10.3748/wjg.v19.i30.4841

Acoustic radiation force impulse of the liver. / D'Onofrio, Mirko; Crosara, Stefano; de Robertis, Riccardo; Canestrini, Stefano; Demozzi, Emanuele; Gallotti, Anna; Pozzi Mucelli, Roberto.

In: World Journal of Gastroenterology, Vol. 19, No. 30, 2013, p. 4841-4849.

Research output: Contribution to journalArticle

D'Onofrio, M, Crosara, S, de Robertis, R, Canestrini, S, Demozzi, E, Gallotti, A & Pozzi Mucelli, R 2013, 'Acoustic radiation force impulse of the liver', World Journal of Gastroenterology, vol. 19, no. 30, pp. 4841-4849. https://doi.org/10.3748/wjg.v19.i30.4841
D'Onofrio M, Crosara S, de Robertis R, Canestrini S, Demozzi E, Gallotti A et al. Acoustic radiation force impulse of the liver. World Journal of Gastroenterology. 2013;19(30):4841-4849. https://doi.org/10.3748/wjg.v19.i30.4841
D'Onofrio, Mirko ; Crosara, Stefano ; de Robertis, Riccardo ; Canestrini, Stefano ; Demozzi, Emanuele ; Gallotti, Anna ; Pozzi Mucelli, Roberto. / Acoustic radiation force impulse of the liver. In: World Journal of Gastroenterology. 2013 ; Vol. 19, No. 30. pp. 4841-4849.
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