Acquired epileptic frontal syndrome as long-term outcome in two children with CSWS

P. Veggiotti, S. Bova, E. Granocchio, G. Papalia, C. Termine, G. Lanzi

Research output: Contribution to journalArticle

Abstract

Continuous spikes and waves during slow sleep (CSWS) are a well-known EEG pattern that can be associated with cognitive and behavioural deterioration. We present the long-term clinical, neuropsychological and EEG follow-up of two patients who developed CSWS during childhood. In both the CSWS onset was followed immediately by rapid cognitive and behavioural deterioration. Later the CSWS fragmented or fluctuated and the spike-wave discharges diminished and this was associated with progressive clinical improvement. At the same time bilateral frontal EEG abnormalities appeared awake and in sleep. After the initial period of rapid cognitive and linguistic improvement both patients stabilised. The latest neuropsychological assessment showed a frontal syndrome. The presence of frontal EEG abnormalities superimposed on CSWS, their persistence after CSWS resolution and, in addition, the finding of subtle frontal-type neuropsychological alterations early in recovery may indicate poor long-term outcome.

Original languageEnglish
Pages (from-to)387-397
Number of pages11
JournalNeurophysiologie Clinique / Clinical Neurophysiology
Volume31
Issue number6
DOIs
Publication statusPublished - 2001

Fingerprint

Sleep
Electroencephalography
Linguistics

Keywords

  • CSWS
  • Frontal EEG abnormalities
  • Long term follow-up
  • Neuropsychology

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Acquired epileptic frontal syndrome as long-term outcome in two children with CSWS. / Veggiotti, P.; Bova, S.; Granocchio, E.; Papalia, G.; Termine, C.; Lanzi, G.

In: Neurophysiologie Clinique / Clinical Neurophysiology, Vol. 31, No. 6, 2001, p. 387-397.

Research output: Contribution to journalArticle

Veggiotti, P. ; Bova, S. ; Granocchio, E. ; Papalia, G. ; Termine, C. ; Lanzi, G. / Acquired epileptic frontal syndrome as long-term outcome in two children with CSWS. In: Neurophysiologie Clinique / Clinical Neurophysiology. 2001 ; Vol. 31, No. 6. pp. 387-397.
@article{4b47466217214c128e6d0d31bcab1b61,
title = "Acquired epileptic frontal syndrome as long-term outcome in two children with CSWS",
abstract = "Continuous spikes and waves during slow sleep (CSWS) are a well-known EEG pattern that can be associated with cognitive and behavioural deterioration. We present the long-term clinical, neuropsychological and EEG follow-up of two patients who developed CSWS during childhood. In both the CSWS onset was followed immediately by rapid cognitive and behavioural deterioration. Later the CSWS fragmented or fluctuated and the spike-wave discharges diminished and this was associated with progressive clinical improvement. At the same time bilateral frontal EEG abnormalities appeared awake and in sleep. After the initial period of rapid cognitive and linguistic improvement both patients stabilised. The latest neuropsychological assessment showed a frontal syndrome. The presence of frontal EEG abnormalities superimposed on CSWS, their persistence after CSWS resolution and, in addition, the finding of subtle frontal-type neuropsychological alterations early in recovery may indicate poor long-term outcome.",
keywords = "CSWS, Frontal EEG abnormalities, Long term follow-up, Neuropsychology",
author = "P. Veggiotti and S. Bova and E. Granocchio and G. Papalia and C. Termine and G. Lanzi",
year = "2001",
doi = "10.1016/S0987-7053(01)00280-5",
language = "English",
volume = "31",
pages = "387--397",
journal = "Neurophysiologie Clinique",
issn = "0987-7053",
publisher = "Elsevier Masson",
number = "6",

}

TY - JOUR

T1 - Acquired epileptic frontal syndrome as long-term outcome in two children with CSWS

AU - Veggiotti, P.

AU - Bova, S.

AU - Granocchio, E.

AU - Papalia, G.

AU - Termine, C.

AU - Lanzi, G.

PY - 2001

Y1 - 2001

N2 - Continuous spikes and waves during slow sleep (CSWS) are a well-known EEG pattern that can be associated with cognitive and behavioural deterioration. We present the long-term clinical, neuropsychological and EEG follow-up of two patients who developed CSWS during childhood. In both the CSWS onset was followed immediately by rapid cognitive and behavioural deterioration. Later the CSWS fragmented or fluctuated and the spike-wave discharges diminished and this was associated with progressive clinical improvement. At the same time bilateral frontal EEG abnormalities appeared awake and in sleep. After the initial period of rapid cognitive and linguistic improvement both patients stabilised. The latest neuropsychological assessment showed a frontal syndrome. The presence of frontal EEG abnormalities superimposed on CSWS, their persistence after CSWS resolution and, in addition, the finding of subtle frontal-type neuropsychological alterations early in recovery may indicate poor long-term outcome.

AB - Continuous spikes and waves during slow sleep (CSWS) are a well-known EEG pattern that can be associated with cognitive and behavioural deterioration. We present the long-term clinical, neuropsychological and EEG follow-up of two patients who developed CSWS during childhood. In both the CSWS onset was followed immediately by rapid cognitive and behavioural deterioration. Later the CSWS fragmented or fluctuated and the spike-wave discharges diminished and this was associated with progressive clinical improvement. At the same time bilateral frontal EEG abnormalities appeared awake and in sleep. After the initial period of rapid cognitive and linguistic improvement both patients stabilised. The latest neuropsychological assessment showed a frontal syndrome. The presence of frontal EEG abnormalities superimposed on CSWS, their persistence after CSWS resolution and, in addition, the finding of subtle frontal-type neuropsychological alterations early in recovery may indicate poor long-term outcome.

KW - CSWS

KW - Frontal EEG abnormalities

KW - Long term follow-up

KW - Neuropsychology

UR - http://www.scopus.com/inward/record.url?scp=0035674876&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035674876&partnerID=8YFLogxK

U2 - 10.1016/S0987-7053(01)00280-5

DO - 10.1016/S0987-7053(01)00280-5

M3 - Article

C2 - 11810988

AN - SCOPUS:0035674876

VL - 31

SP - 387

EP - 397

JO - Neurophysiologie Clinique

JF - Neurophysiologie Clinique

SN - 0987-7053

IS - 6

ER -