Acquired immunodeficiency syndrome-related cancer. A study model for the mechanisms contributing to the genesis of cancer

A. Carbone, G. Gaidano

Research output: Contribution to journalArticle

Abstract

The study of AIDS and cancer has resulted in an important convergence of clinical-epidemiological investigations, molecular research and virological studies. This shared effort has led to significant discoveries in the field of human carcinogenesis. In a relatively short time, several topics have been clarified, namely: The spectrum of AIDS-related tumours has been identified; The role of HIV in lymphomagenesis and in the development of Kaposi's sarcoma (KS) has been defined; AIDS-related cancers have allowed the discovery and extensive biological characterisation of the novel virus human herpes virus type 8 (HHV8), also called KS-associated herpesvirus; Genetic, molecular and phenotypic studies of AIDS-related lymphomas have contributed to the formulation of a pathogenetic and histogenetic model of B-cell non-Hodgkin's lymphomas (NHL).

Original languageEnglish
Pages (from-to)1184-1187
Number of pages4
JournalEuropean Journal of Cancer
Volume37
Issue number10
DOIs
Publication statusPublished - 2001

Keywords

  • AIDS
  • Cancer
  • Human carcinogenesis
  • Lymphomagenesis

ASJC Scopus subject areas

  • Cancer Research
  • Hematology
  • Oncology

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