TY - JOUR
T1 - Acquired immunodeficiency syndrome-related cancer. A study model for the mechanisms contributing to the genesis of cancer
AU - Carbone, A.
AU - Gaidano, G.
PY - 2001
Y1 - 2001
N2 - The study of AIDS and cancer has resulted in an important convergence of clinical-epidemiological investigations, molecular research and virological studies. This shared effort has led to significant discoveries in the field of human carcinogenesis. In a relatively short time, several topics have been clarified, namely: The spectrum of AIDS-related tumours has been identified; The role of HIV in lymphomagenesis and in the development of Kaposi's sarcoma (KS) has been defined; AIDS-related cancers have allowed the discovery and extensive biological characterisation of the novel virus human herpes virus type 8 (HHV8), also called KS-associated herpesvirus; Genetic, molecular and phenotypic studies of AIDS-related lymphomas have contributed to the formulation of a pathogenetic and histogenetic model of B-cell non-Hodgkin's lymphomas (NHL).
AB - The study of AIDS and cancer has resulted in an important convergence of clinical-epidemiological investigations, molecular research and virological studies. This shared effort has led to significant discoveries in the field of human carcinogenesis. In a relatively short time, several topics have been clarified, namely: The spectrum of AIDS-related tumours has been identified; The role of HIV in lymphomagenesis and in the development of Kaposi's sarcoma (KS) has been defined; AIDS-related cancers have allowed the discovery and extensive biological characterisation of the novel virus human herpes virus type 8 (HHV8), also called KS-associated herpesvirus; Genetic, molecular and phenotypic studies of AIDS-related lymphomas have contributed to the formulation of a pathogenetic and histogenetic model of B-cell non-Hodgkin's lymphomas (NHL).
KW - AIDS
KW - Cancer
KW - Human carcinogenesis
KW - Lymphomagenesis
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U2 - 10.1016/S0959-8049(01)00102-2
DO - 10.1016/S0959-8049(01)00102-2
M3 - Article
C2 - 11423250
AN - SCOPUS:0034968442
VL - 37
SP - 1184
EP - 1187
JO - European Journal of Cancer
JF - European Journal of Cancer
SN - 0959-8049
IS - 10
ER -