Actin in membrane trafficking

Research output: Contribution to journalArticle

Abstract

Actin cytoskeleton remodeling provides the forces required for a variety of cellular processes based on membrane dynamics, such as endocytosis, exocytosis, and vesicular trafficking at the Golgi. All these events are coordinated by networks of associated proteins, and some of them are functionally connected with cell migration. The site and the duration of actin polymerization, in connection with vesicle budding and fusion, are tightly controlled by both small GTPases and the large GTPase dynamin. Recent advances in the understanding of the mechanisms coupling actin dynamics with membrane trafficking at the cell surface have been brought by the combined studies of actin polymerizing factors and of the endocytic/exocytic machinery.

Original languageEnglish
Pages (from-to)453-458
Number of pages6
JournalCurrent Opinion in Cell Biology
Volume19
Issue number4
DOIs
Publication statusPublished - Aug 2007

ASJC Scopus subject areas

  • Cell Biology

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