Abstract
Actinobacteria are one the four major phyla of the gut microbiota and, although they represent only a small percentage, are pivotal in the maintenance of gut homeostasis. During the last decade many studies focused the attention on Actinobacteria, especially on their role both in gastrointestinal and systemic diseases and on their possible therapeutic use. In fact, classes of this phylum, especially Bifidobacteria, are widely used as probiotic demonstrating beneficial effects in many pathological conditions, even if larger in vivo studies are needed to confirm such encouraging results. This review aims to explore the current knowledge on their physiological functions and to speculate on their possible therapeutic role(s) in gastrointestinal and systemic diseases.
| Original language | English |
|---|---|
| Pages (from-to) | 421-428 |
| Number of pages | 8 |
| Journal | Digestive and Liver Disease |
| Volume | 50 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - May 1 2018 |
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Keywords
- Actinobacteria
- Bifidobacteria spp.
- Dysbiosis
- Gut homeostasis
- Gut microbiota
- Probiotic
ASJC Scopus subject areas
- Hepatology
- Gastroenterology
Cite this
Actinobacteria : A relevant minority for the maintenance of gut homeostasis. / Binda, Cecilia; Lopetuso, Loris Riccardo; Rizzatti, Gianenrico; Gibiino, Giulia; Cennamo, Vincenzo; Gasbarrini, Antonio.
In: Digestive and Liver Disease, Vol. 50, No. 5, 01.05.2018, p. 421-428.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Actinobacteria
T2 - A relevant minority for the maintenance of gut homeostasis
AU - Binda, Cecilia
AU - Lopetuso, Loris Riccardo
AU - Rizzatti, Gianenrico
AU - Gibiino, Giulia
AU - Cennamo, Vincenzo
AU - Gasbarrini, Antonio
PY - 2018/5/1
Y1 - 2018/5/1
N2 - Actinobacteria are one the four major phyla of the gut microbiota and, although they represent only a small percentage, are pivotal in the maintenance of gut homeostasis. During the last decade many studies focused the attention on Actinobacteria, especially on their role both in gastrointestinal and systemic diseases and on their possible therapeutic use. In fact, classes of this phylum, especially Bifidobacteria, are widely used as probiotic demonstrating beneficial effects in many pathological conditions, even if larger in vivo studies are needed to confirm such encouraging results. This review aims to explore the current knowledge on their physiological functions and to speculate on their possible therapeutic role(s) in gastrointestinal and systemic diseases.
AB - Actinobacteria are one the four major phyla of the gut microbiota and, although they represent only a small percentage, are pivotal in the maintenance of gut homeostasis. During the last decade many studies focused the attention on Actinobacteria, especially on their role both in gastrointestinal and systemic diseases and on their possible therapeutic use. In fact, classes of this phylum, especially Bifidobacteria, are widely used as probiotic demonstrating beneficial effects in many pathological conditions, even if larger in vivo studies are needed to confirm such encouraging results. This review aims to explore the current knowledge on their physiological functions and to speculate on their possible therapeutic role(s) in gastrointestinal and systemic diseases.
KW - Actinobacteria
KW - Bifidobacteria spp.
KW - Dysbiosis
KW - Gut homeostasis
KW - Gut microbiota
KW - Probiotic
UR - http://www.scopus.com/inward/record.url?scp=85044124742&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85044124742&partnerID=8YFLogxK
U2 - 10.1016/j.dld.2018.02.012
DO - 10.1016/j.dld.2018.02.012
M3 - Review article
C2 - 29567414
AN - SCOPUS:85044124742
VL - 50
SP - 421
EP - 428
JO - Digestive and Liver Disease
JF - Digestive and Liver Disease
SN - 1590-8658
IS - 5
ER -