Action and object naming in physiological aging: An rTMS study

Maria Cotelli, Rosa Manenti, Sandra Rosini, Marco Calabria, Michela Brambilla, Patrizia Silvia Bisiacchi, Orazio Zanetti, Carlo Miniussi

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Word-retrieval difficulties commonly occur in healthy aging. Recent studies report an improved ability to name pictures after the administration of high-frequency repetitive transcranial magnetic stimulation (rTMS) in healthy younger adults and in patients with neurological disease. The aim of this study was to assess the effect of high-frequency rTMS applied to the dorsolateral prefrontal cortex (DLPFC) on picture naming in healthy older adults. High-frequency rTMS was applied to the left and right DLPFC during object and action naming in 13 healthy older adults. The naming latency for actions was shortened after stimulation of the left and right DLPFC compared to application of the sham stimulation. Stimulation was not observed to have any effect on correctness of naming. Our data demonstrate the involvement of the left and right DLPFC in a sample of healthy aging subjects during an action-naming task. The bilateral involvement of the DLPFC in these participants is discussed together with data on younger adults and on Alzheimer's patients.

Original languageEnglish
Article numberArticle 151
JournalFrontiers in Aging Neuroscience
Volume2
Issue numberNOV
DOIs
Publication statusPublished - 2010

Fingerprint

Transcranial Magnetic Stimulation
Prefrontal Cortex
Young Adult
Names
Healthy Volunteers

Keywords

  • Brain stimulation
  • HAROLD
  • Naming

ASJC Scopus subject areas

  • Ageing
  • Cognitive Neuroscience

Cite this

Cotelli, M., Manenti, R., Rosini, S., Calabria, M., Brambilla, M., Bisiacchi, P. S., ... Miniussi, C. (2010). Action and object naming in physiological aging: An rTMS study. Frontiers in Aging Neuroscience, 2(NOV), [Article 151]. https://doi.org/10.3389/fnagi.2010.00151

Action and object naming in physiological aging : An rTMS study. / Cotelli, Maria; Manenti, Rosa; Rosini, Sandra; Calabria, Marco; Brambilla, Michela; Bisiacchi, Patrizia Silvia; Zanetti, Orazio; Miniussi, Carlo.

In: Frontiers in Aging Neuroscience, Vol. 2, No. NOV, Article 151, 2010.

Research output: Contribution to journalArticle

Cotelli, Maria ; Manenti, Rosa ; Rosini, Sandra ; Calabria, Marco ; Brambilla, Michela ; Bisiacchi, Patrizia Silvia ; Zanetti, Orazio ; Miniussi, Carlo. / Action and object naming in physiological aging : An rTMS study. In: Frontiers in Aging Neuroscience. 2010 ; Vol. 2, No. NOV.
@article{cc4b75e0e76342b49d245396933067a4,
title = "Action and object naming in physiological aging: An rTMS study",
abstract = "Word-retrieval difficulties commonly occur in healthy aging. Recent studies report an improved ability to name pictures after the administration of high-frequency repetitive transcranial magnetic stimulation (rTMS) in healthy younger adults and in patients with neurological disease. The aim of this study was to assess the effect of high-frequency rTMS applied to the dorsolateral prefrontal cortex (DLPFC) on picture naming in healthy older adults. High-frequency rTMS was applied to the left and right DLPFC during object and action naming in 13 healthy older adults. The naming latency for actions was shortened after stimulation of the left and right DLPFC compared to application of the sham stimulation. Stimulation was not observed to have any effect on correctness of naming. Our data demonstrate the involvement of the left and right DLPFC in a sample of healthy aging subjects during an action-naming task. The bilateral involvement of the DLPFC in these participants is discussed together with data on younger adults and on Alzheimer's patients.",
keywords = "Brain stimulation, HAROLD, Naming",
author = "Maria Cotelli and Rosa Manenti and Sandra Rosini and Marco Calabria and Michela Brambilla and Bisiacchi, {Patrizia Silvia} and Orazio Zanetti and Carlo Miniussi",
year = "2010",
doi = "10.3389/fnagi.2010.00151",
language = "English",
volume = "2",
journal = "Frontiers in Aging Neuroscience",
issn = "1663-4365",
publisher = "Frontiers Research Foundation",
number = "NOV",

}

TY - JOUR

T1 - Action and object naming in physiological aging

T2 - An rTMS study

AU - Cotelli, Maria

AU - Manenti, Rosa

AU - Rosini, Sandra

AU - Calabria, Marco

AU - Brambilla, Michela

AU - Bisiacchi, Patrizia Silvia

AU - Zanetti, Orazio

AU - Miniussi, Carlo

PY - 2010

Y1 - 2010

N2 - Word-retrieval difficulties commonly occur in healthy aging. Recent studies report an improved ability to name pictures after the administration of high-frequency repetitive transcranial magnetic stimulation (rTMS) in healthy younger adults and in patients with neurological disease. The aim of this study was to assess the effect of high-frequency rTMS applied to the dorsolateral prefrontal cortex (DLPFC) on picture naming in healthy older adults. High-frequency rTMS was applied to the left and right DLPFC during object and action naming in 13 healthy older adults. The naming latency for actions was shortened after stimulation of the left and right DLPFC compared to application of the sham stimulation. Stimulation was not observed to have any effect on correctness of naming. Our data demonstrate the involvement of the left and right DLPFC in a sample of healthy aging subjects during an action-naming task. The bilateral involvement of the DLPFC in these participants is discussed together with data on younger adults and on Alzheimer's patients.

AB - Word-retrieval difficulties commonly occur in healthy aging. Recent studies report an improved ability to name pictures after the administration of high-frequency repetitive transcranial magnetic stimulation (rTMS) in healthy younger adults and in patients with neurological disease. The aim of this study was to assess the effect of high-frequency rTMS applied to the dorsolateral prefrontal cortex (DLPFC) on picture naming in healthy older adults. High-frequency rTMS was applied to the left and right DLPFC during object and action naming in 13 healthy older adults. The naming latency for actions was shortened after stimulation of the left and right DLPFC compared to application of the sham stimulation. Stimulation was not observed to have any effect on correctness of naming. Our data demonstrate the involvement of the left and right DLPFC in a sample of healthy aging subjects during an action-naming task. The bilateral involvement of the DLPFC in these participants is discussed together with data on younger adults and on Alzheimer's patients.

KW - Brain stimulation

KW - HAROLD

KW - Naming

UR - http://www.scopus.com/inward/record.url?scp=84856760368&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84856760368&partnerID=8YFLogxK

U2 - 10.3389/fnagi.2010.00151

DO - 10.3389/fnagi.2010.00151

M3 - Article

AN - SCOPUS:84856760368

VL - 2

JO - Frontiers in Aging Neuroscience

JF - Frontiers in Aging Neuroscience

SN - 1663-4365

IS - NOV

M1 - Article 151

ER -