Active and inactive renin throughout high risk pregnancy

G. C. Ambroso, A. Morganti, G. Como, A. Masa, G. B. Candiani, F. Polvani

Research output: Contribution to journalArticlepeer-review


Women with history of pregnancy induced hypertension (PIH) and/or unexplained foetal loss have a greater prevalence of high risk pregnancy. Since recent studies suggest that changes in the activity of the renin system may be important in complicated pregnancy, we have determined active (AR) and inactive (IR) renin (by enzymatic method, ng/ml/h) in 36 women (age 30.7 ± 5.7) with history of PIH or foetal loss. Blood samples were collected monthly throughout pregnancy. Ten patients (pts) showed a significant fall in active renin (

Original languageEnglish
Pages (from-to)75-87
Number of pages13
JournalHypertension in Pregnancy
Issue number1-2
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Internal Medicine


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