Active or recent parvovirus B19 infection in children with Kawasaki disease

G. Nigro, A. Krzysztofiak, M. A. Porcaro, T. Mango, M. Zerbini, G. Gentilomi, M. Musiani

Research output: Contribution to journalArticle

Abstract

Because parvovirus B19 occasionally causes some of the features typical of Kawasaki disease, we investigated B19 involvement in 15 children with Kawasaki disease. Active or recent B19 infection, as shown by B19-DNAaemia, positive B19-specific IgM antibodies, or both, was diagnosed in 10 patients (67%). A high frequency of all major criteria for diagnosis of Kawasaki disease (60%), anaemia (60%), coronary aneurysms (30%), and arthropathy (30%) was found in children with B19-associated Kawasaki disease. Thus B19 may have a pathogenic role in the development of Kawasaki disease, with other predisposing factors.

Original languageEnglish
Pages (from-to)1260-1261
Number of pages2
JournalLancet
Volume343
Issue number8908
DOIs
Publication statusPublished - May 21 1994

ASJC Scopus subject areas

  • Medicine(all)

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    Nigro, G., Krzysztofiak, A., Porcaro, M. A., Mango, T., Zerbini, M., Gentilomi, G., & Musiani, M. (1994). Active or recent parvovirus B19 infection in children with Kawasaki disease. Lancet, 343(8908), 1260-1261. https://doi.org/10.1016/S0140-6736(94)92154-7