Active or recent parvovirus B19 infection in children with Kawasaki disease

G. Nigro, A. Krzysztofiak, M. A. Porcaro, T. Mango, M. Zerbini, G. Gentilomi, M. Musiani

Research output: Contribution to journalArticle

116 Citations (Scopus)

Abstract

Because parvovirus B19 occasionally causes some of the features typical of Kawasaki disease, we investigated B19 involvement in 15 children with Kawasaki disease. Active or recent B19 infection, as shown by B19-DNAaemia, positive B19-specific IgM antibodies, or both, was diagnosed in 10 patients (67%). A high frequency of all major criteria for diagnosis of Kawasaki disease (60%), anaemia (60%), coronary aneurysms (30%), and arthropathy (30%) was found in children with B19-associated Kawasaki disease. Thus B19 may have a pathogenic role in the development of Kawasaki disease, with other predisposing factors.

Original languageEnglish
Pages (from-to)1260-1261
Number of pages2
JournalLancet
Volume343
Issue number8908
DOIs
Publication statusPublished - May 21 1994

Fingerprint

Parvoviridae Infections
Mucocutaneous Lymph Node Syndrome
Coronary Aneurysm
Parvovirus
Joint Diseases
Causality
Immunoglobulin M
Anemia
Antibodies
Infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Nigro, G., Krzysztofiak, A., Porcaro, M. A., Mango, T., Zerbini, M., Gentilomi, G., & Musiani, M. (1994). Active or recent parvovirus B19 infection in children with Kawasaki disease. Lancet, 343(8908), 1260-1261. https://doi.org/10.1016/S0140-6736(94)92154-7

Active or recent parvovirus B19 infection in children with Kawasaki disease. / Nigro, G.; Krzysztofiak, A.; Porcaro, M. A.; Mango, T.; Zerbini, M.; Gentilomi, G.; Musiani, M.

In: Lancet, Vol. 343, No. 8908, 21.05.1994, p. 1260-1261.

Research output: Contribution to journalArticle

Nigro, G, Krzysztofiak, A, Porcaro, MA, Mango, T, Zerbini, M, Gentilomi, G & Musiani, M 1994, 'Active or recent parvovirus B19 infection in children with Kawasaki disease', Lancet, vol. 343, no. 8908, pp. 1260-1261. https://doi.org/10.1016/S0140-6736(94)92154-7
Nigro G, Krzysztofiak A, Porcaro MA, Mango T, Zerbini M, Gentilomi G et al. Active or recent parvovirus B19 infection in children with Kawasaki disease. Lancet. 1994 May 21;343(8908):1260-1261. https://doi.org/10.1016/S0140-6736(94)92154-7
Nigro, G. ; Krzysztofiak, A. ; Porcaro, M. A. ; Mango, T. ; Zerbini, M. ; Gentilomi, G. ; Musiani, M. / Active or recent parvovirus B19 infection in children with Kawasaki disease. In: Lancet. 1994 ; Vol. 343, No. 8908. pp. 1260-1261.
@article{059fa0dddca04229aa7912dee80ab788,
title = "Active or recent parvovirus B19 infection in children with Kawasaki disease",
abstract = "Because parvovirus B19 occasionally causes some of the features typical of Kawasaki disease, we investigated B19 involvement in 15 children with Kawasaki disease. Active or recent B19 infection, as shown by B19-DNAaemia, positive B19-specific IgM antibodies, or both, was diagnosed in 10 patients (67{\%}). A high frequency of all major criteria for diagnosis of Kawasaki disease (60{\%}), anaemia (60{\%}), coronary aneurysms (30{\%}), and arthropathy (30{\%}) was found in children with B19-associated Kawasaki disease. Thus B19 may have a pathogenic role in the development of Kawasaki disease, with other predisposing factors.",
author = "G. Nigro and A. Krzysztofiak and Porcaro, {M. A.} and T. Mango and M. Zerbini and G. Gentilomi and M. Musiani",
year = "1994",
month = "5",
day = "21",
doi = "10.1016/S0140-6736(94)92154-7",
language = "English",
volume = "343",
pages = "1260--1261",
journal = "The Lancet",
issn = "0140-6736",
publisher = "Lancet Publishing Group",
number = "8908",

}

TY - JOUR

T1 - Active or recent parvovirus B19 infection in children with Kawasaki disease

AU - Nigro, G.

AU - Krzysztofiak, A.

AU - Porcaro, M. A.

AU - Mango, T.

AU - Zerbini, M.

AU - Gentilomi, G.

AU - Musiani, M.

PY - 1994/5/21

Y1 - 1994/5/21

N2 - Because parvovirus B19 occasionally causes some of the features typical of Kawasaki disease, we investigated B19 involvement in 15 children with Kawasaki disease. Active or recent B19 infection, as shown by B19-DNAaemia, positive B19-specific IgM antibodies, or both, was diagnosed in 10 patients (67%). A high frequency of all major criteria for diagnosis of Kawasaki disease (60%), anaemia (60%), coronary aneurysms (30%), and arthropathy (30%) was found in children with B19-associated Kawasaki disease. Thus B19 may have a pathogenic role in the development of Kawasaki disease, with other predisposing factors.

AB - Because parvovirus B19 occasionally causes some of the features typical of Kawasaki disease, we investigated B19 involvement in 15 children with Kawasaki disease. Active or recent B19 infection, as shown by B19-DNAaemia, positive B19-specific IgM antibodies, or both, was diagnosed in 10 patients (67%). A high frequency of all major criteria for diagnosis of Kawasaki disease (60%), anaemia (60%), coronary aneurysms (30%), and arthropathy (30%) was found in children with B19-associated Kawasaki disease. Thus B19 may have a pathogenic role in the development of Kawasaki disease, with other predisposing factors.

UR - http://www.scopus.com/inward/record.url?scp=0028304951&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028304951&partnerID=8YFLogxK

U2 - 10.1016/S0140-6736(94)92154-7

DO - 10.1016/S0140-6736(94)92154-7

M3 - Article

C2 - 7910278

AN - SCOPUS:0028304951

VL - 343

SP - 1260

EP - 1261

JO - The Lancet

JF - The Lancet

SN - 0140-6736

IS - 8908

ER -