Activity of cytokine-induced killer cells against bone and soft tissue sarcoma

Research output: Contribution to journalArticle

Abstract

Cytokine-induced killer (CIK) cells are T lymphocytes expanded ex vivo that are endowed with MHC-independent tumoricidal activity. We have recently demonstrated, in a preclinical setting, that CIK cells are active against autologous bone and soft tissue sarcomas. In particular, CIK cells killed a putative sarcoma stem cell population that may underlie disease relapse and chemoresistance.

Original languageEnglish
Article numbere28269
JournalOncoImmunology
Volume3
Issue number3
DOIs
Publication statusPublished - 2014

Keywords

  • Adoptive immunotherapy
  • Cancer stem cells
  • CIK cells
  • Sarcomas
  • Solid tumors

ASJC Scopus subject areas

  • Immunology and Allergy
  • Oncology
  • Immunology

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