TY - JOUR
T1 - Acute aortic dissections with entry tear in the arch
T2 - A report from the International Registry of Acute Aortic Dissection
AU - Trimarchi, Santi
AU - de Beaufort, Hector W.L.
AU - Tolenaar, Jip L.
AU - Bavaria, Joseph E.
AU - Desai, Nimesh D.
AU - Di Eusanio, Marco
AU - Di Bartolomeo, Roberto
AU - Peterson, Mark D.
AU - Ehrlich, Marek
AU - Evangelista, Arturo
AU - Montgomery, Daniel G.
AU - Myrmel, Truls
AU - Hughes, G. Chad
AU - Appoo, Jehangir J.
AU - De Vincentiis, Carlo
AU - Yan, Tristan D.
AU - Nienaber, Christoph A.
AU - Isselbacher, Eric M.
AU - Deeb, G. Michael
AU - Gleason, Thomas G.
AU - Patel, Himanshu J.
AU - Sundt, Thoralf M.
AU - Eagle, Kim A.
PY - 2019/1
Y1 - 2019/1
N2 - Objective: To analyze presentation, management, and outcomes of acute aortic dissections with proximal entry tear in the arch. Methods: Patients enrolled in the International Registry of Acute Aortic Dissection and entry tear in the arch were classified into 2 groups: arch A (retrograde extension into the ascending aorta with or without antegrade extension) and arch B (only antegrade extension into the descending aorta or further distally). Presentation, management, and in-hospital outcomes of the 2 groups were compared. Results: The arch A (n = 228) and arch B (n = 140) groups were similar concerning the presence of any preoperative complication (68.4% vs 60.0%; P =.115), but the types of complication were different. Arch A presented more commonly with shock, neurologic complications, cardiac tamponade, and grade 3 or 4 aortic valve insufficiency and less frequently with refractory hypertension, visceral ischemia, extension of dissection, and aortic rupture. Management for both groups were open surgery (77.6% vs 18.6%; P <.001), endovascular treatment (3.5% vs 25.0%; P <.001), and medical management (16.2% vs 51.4%; P <.001). Overall in-hospital mortality was similar (16.7% vs 19.3%; P =.574), but mortality tended to be lower in the arch A group after open surgery (15.3% vs 30.8%; P =.090), and higher after endovascular (25.0% vs 14.3%; P =.597) or medical treatment (24.3% vs 13.9%; P =.191), although the differences were not significant. Conclusions: Acute aortic dissection patients with primary entry tear in the arch are currently managed by a patient-specific approach. In choosing the management type of these patients, it may be advisable to stratify them based on retrograde or only antegrade extension of the dissection.
AB - Objective: To analyze presentation, management, and outcomes of acute aortic dissections with proximal entry tear in the arch. Methods: Patients enrolled in the International Registry of Acute Aortic Dissection and entry tear in the arch were classified into 2 groups: arch A (retrograde extension into the ascending aorta with or without antegrade extension) and arch B (only antegrade extension into the descending aorta or further distally). Presentation, management, and in-hospital outcomes of the 2 groups were compared. Results: The arch A (n = 228) and arch B (n = 140) groups were similar concerning the presence of any preoperative complication (68.4% vs 60.0%; P =.115), but the types of complication were different. Arch A presented more commonly with shock, neurologic complications, cardiac tamponade, and grade 3 or 4 aortic valve insufficiency and less frequently with refractory hypertension, visceral ischemia, extension of dissection, and aortic rupture. Management for both groups were open surgery (77.6% vs 18.6%; P <.001), endovascular treatment (3.5% vs 25.0%; P <.001), and medical management (16.2% vs 51.4%; P <.001). Overall in-hospital mortality was similar (16.7% vs 19.3%; P =.574), but mortality tended to be lower in the arch A group after open surgery (15.3% vs 30.8%; P =.090), and higher after endovascular (25.0% vs 14.3%; P =.597) or medical treatment (24.3% vs 13.9%; P =.191), although the differences were not significant. Conclusions: Acute aortic dissection patients with primary entry tear in the arch are currently managed by a patient-specific approach. In choosing the management type of these patients, it may be advisable to stratify them based on retrograde or only antegrade extension of the dissection.
KW - acute aortic syndrome
KW - aortic dissection
KW - aortic surgery
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U2 - 10.1016/j.jtcvs.2018.07.101
DO - 10.1016/j.jtcvs.2018.07.101
M3 - Article
C2 - 30396735
AN - SCOPUS:85055907139
VL - 157
SP - 66
EP - 73
JO - Journal of Thoracic and Cardiovascular Surgery
JF - Journal of Thoracic and Cardiovascular Surgery
SN - 0022-5223
IS - 1
ER -