Acute Cytomegalovirus Infection as a Cause of Venous Thromboembolism

Francesca Rinaldi, Raffaella Lissandrin, Francesco Mojoli, Fausto Baldanti, Enrico Brunetti, Michela Pascarella, Maria Teresa Giordani

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Acute Human Cytomegalovirus (HCMV) infection is an unusual cause of venous thromboembolism, a potentially life-threatening condition. Thrombus formation can occur at the onset of the disease or later during the recovery and may also occur in the absence of acute HCMV hepatitis. It is likely due to both vascular endothelium damage caused by HCMV and impairment of the clotting balance caused by the virus itself. Here we report on two immunocompetent women with splanchnic thrombosis that occurred during the course of acute HCMV infection. Although the prevalence of venous thrombosis in patients with acute HCMV infection is unknown, physicians should be aware of its occurrence, particularly in immunocompetent patients presenting with fever and unexplained abdominal pain.

Original languageEnglish
Article numbere2014041
JournalMediterranean Journal of Hematology and Infectious Diseases
Issue number1
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Hematology
  • Infectious Diseases


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