Abstract
Sporadic descriptions of acute onset of watery diarrhea within a few hours to a few weeks azathioprine administration beginning have been reported, particularly in inflammatory bowel disease patients. This article reports the case of a woman treated with azathioprine because of type I autoimmune hepatitis, who developed acute watery diarrheaafter more than two months of therapy. In two occasions the patient reassumed the drug and in a few hours diarrhearecurred. Subsequent 6-mercaptopurine treatment was well tolerated, suggesting that the previous side-effect could be due to the nitroimidazole moiety of azathioprine.
Original language | English |
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Pages (from-to) | 219-222 |
Number of pages | 4 |
Journal | Minerva Medica |
Volume | 99 |
Issue number | 2 |
Publication status | Published - Apr 2008 |
Keywords
- 6-Mercaptopurine
- Azathioprine
- Diarrhea
- Hepatitis, autoimmune
ASJC Scopus subject areas
- Medicine(all)