Acute effects of peritoneovenous shunt (Le Veen) on the hemodynamics and gas exchange in patients with hepatic intractable ascites

L. S. Brandi, M. Grana, F. D'Elia, M. Ferrari, M. Oleggini, M. Carmellini, A. Pietrabissa, F. Mosca

Research output: Contribution to journalArticlepeer-review

Abstract

The acute effects of the peritoneovenous shunt (LeVeen) on hemodynamics and pulmonary gas exchange in 6 consecutive patients with intractable ascites and cirrhosis were evaluated. After opening the peritoneovenous shunt, there was a marked increase in cardiac index, (from 3.78 ± 0.4 to 5.86 ± 0.4 l/min. m2, p <0.01), and mean pulmonary artery pressure (from 17.3 ± 1.9 to 23.3 ± 1.5 mmHg, p <0.05), while a significant decrease in systemic vascular resistances (from 1086 ± 116 to 694 ± 52 dynes.sec. cm-5, p <0.05) was observed. In all patients there was a drop in arterial oxygen tension (P(a)O2) (from 76 ± 3 to 67 ± 3 torr, p <0.01) and an increase in venous admixture (QS(p)/Qt) from 13.1 ± 2 to 18.9 ± 2%, p <0.01). The comparable increase in cardiac output and in venous admixture produced by opening the peritoneovenous shunt, might be related to the massive transfusion of ascitic fluid into the intravascular compartment. It is therefore concluded that this impairment of tas exchange further support discarding an appropriate amount of ascitic fluid at the time of shunt insertion.

Original languageEnglish
Pages (from-to)137-142
Number of pages6
JournalItalian Journal of Surgical Sciences
Volume18
Issue number2
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Surgery

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