Acute gangrene of the scrotum and penis in four hematologic patients. The usefulness of hyperbaric oxygen therapy in one case

F. Radaelli, A. della Volpe, M. Colombi, P. Bregani, E. E. Polli

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Abstract

We describe four cases of Fournier's gangrene complicating the postchemotherapy aplastic phase (polymorphonuclear cells [PMN] <500/μl) in three patients with acute leukemia and one patient with non-Hodgkin's lymphoma. Blood and local cultures from two patients contained Pseudomonas aeruginosa, and local cultures from another patient grew both P. aeruginosa and Proteus rettgeri. Early recognition of aggressive antibiotic and surgical treatment with granulocyte recovery were fundamental factors in resolution of the gangrene in three of the four patients. Hyperbaric oxygen therapy, never reported in hematologic patients, was also very useful in one patients in whom the clinical course was particularly acute.

Original languageEnglish
Pages (from-to)1462-1464
Number of pages3
JournalCancer
Volume60
Issue number7
Publication statusPublished - 1987

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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    Radaelli, F., della Volpe, A., Colombi, M., Bregani, P., & Polli, E. E. (1987). Acute gangrene of the scrotum and penis in four hematologic patients. The usefulness of hyperbaric oxygen therapy in one case. Cancer, 60(7), 1462-1464.