Acute hepatitis associated with clopidogrel: A case report and review of the literature

Raffaella Pisapia, Amina Abdeddaim, Andrea Mariano, Alessia Rianda, Laura Vincenzi, Chiara Taibi, Andrea Baiocchini, Franca Del Nonno, Gianpiero D'Offizi

Research output: Contribution to journalArticlepeer-review

Abstract

Drug-induced hepatotoxicity is a common cause of acute hepatitis, and the recognition of the responsible drug may be difficult. We describe a case of clopidogrel-related acute hepatitis. The diagnosis is strongly suggested by an accurate medical history and liver biopsy. Reports about cases of hepatotoxicity due to clopidogrel are increasing in the last few years, after the increased use of this drug. In conclusion, we believe that physicians should carefully consider the risk of drug-induced hepatic injury when clopidogrel is prescribed.

Original languageEnglish
Pages (from-to)e8-e13
JournalAmerican Journal of Therapeutics
Volume22
Issue number1
DOIs
Publication statusPublished - Jan 21 2015

Keywords

  • clopidogrel
  • Drug-induced hepatotoxicity
  • liver biopsy
  • medical history

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Medicine(all)

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