Abstract
Drug-induced hepatotoxicity is a common cause of acute hepatitis, and the recognition of the responsible drug may be difficult. We describe a case of clopidogrel-related acute hepatitis. The diagnosis is strongly suggested by an accurate medical history and liver biopsy. Reports about cases of hepatotoxicity due to clopidogrel are increasing in the last few years, after the increased use of this drug. In conclusion, we believe that physicians should carefully consider the risk of drug-induced hepatic injury when clopidogrel is prescribed.
| Original language | English |
|---|---|
| Pages (from-to) | e8-e13 |
| Journal | American Journal of Therapeutics |
| Volume | 22 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 21 2015 |
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Keywords
- clopidogrel
- Drug-induced hepatotoxicity
- liver biopsy
- medical history
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)
- Medicine(all)
Cite this
Acute hepatitis associated with clopidogrel : A case report and review of the literature. / Pisapia, Raffaella; Abdeddaim, Amina; Mariano, Andrea; Rianda, Alessia; Vincenzi, Laura; Taibi, Chiara; Baiocchini, Andrea; Del Nonno, Franca; D'Offizi, Gianpiero.
In: American Journal of Therapeutics, Vol. 22, No. 1, 21.01.2015, p. e8-e13.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Acute hepatitis associated with clopidogrel
T2 - A case report and review of the literature
AU - Pisapia, Raffaella
AU - Abdeddaim, Amina
AU - Mariano, Andrea
AU - Rianda, Alessia
AU - Vincenzi, Laura
AU - Taibi, Chiara
AU - Baiocchini, Andrea
AU - Del Nonno, Franca
AU - D'Offizi, Gianpiero
PY - 2015/1/21
Y1 - 2015/1/21
N2 - Drug-induced hepatotoxicity is a common cause of acute hepatitis, and the recognition of the responsible drug may be difficult. We describe a case of clopidogrel-related acute hepatitis. The diagnosis is strongly suggested by an accurate medical history and liver biopsy. Reports about cases of hepatotoxicity due to clopidogrel are increasing in the last few years, after the increased use of this drug. In conclusion, we believe that physicians should carefully consider the risk of drug-induced hepatic injury when clopidogrel is prescribed.
AB - Drug-induced hepatotoxicity is a common cause of acute hepatitis, and the recognition of the responsible drug may be difficult. We describe a case of clopidogrel-related acute hepatitis. The diagnosis is strongly suggested by an accurate medical history and liver biopsy. Reports about cases of hepatotoxicity due to clopidogrel are increasing in the last few years, after the increased use of this drug. In conclusion, we believe that physicians should carefully consider the risk of drug-induced hepatic injury when clopidogrel is prescribed.
KW - clopidogrel
KW - Drug-induced hepatotoxicity
KW - liver biopsy
KW - medical history
UR - http://www.scopus.com/inward/record.url?scp=84921436204&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84921436204&partnerID=8YFLogxK
U2 - 10.1097/MJT.0b013e318293b0d6
DO - 10.1097/MJT.0b013e318293b0d6
M3 - Article
C2 - 23846525
AN - SCOPUS:84921436204
VL - 22
SP - e8-e13
JO - American Journal of Therapeutics
JF - American Journal of Therapeutics
SN - 1075-2765
IS - 1
ER -