Acute hepatitis associated with clopidogrel: A case report and review of the literature

Raffaella Pisapia; Amina Abdeddaim; Andrea Mariano; Alessia Rianda; Laura Vincenzi; Chiara Taibi; Andrea Baiocchini; Franca Del Nonno; Gianpiero D'Offizi

doi:10.1097/MJT.0b013e318293b0d6

Acute hepatitis associated with clopidogrel: A case report and review of the literature

Raffaella Pisapia, Amina Abdeddaim, Andrea Mariano, Alessia Rianda, Laura Vincenzi, Chiara Taibi, Andrea Baiocchini, Franca Del Nonno, Gianpiero D'Offizi

Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani

Research output: Contribution to journal › Article › peer-review

Abstract

Drug-induced hepatotoxicity is a common cause of acute hepatitis, and the recognition of the responsible drug may be difficult. We describe a case of clopidogrel-related acute hepatitis. The diagnosis is strongly suggested by an accurate medical history and liver biopsy. Reports about cases of hepatotoxicity due to clopidogrel are increasing in the last few years, after the increased use of this drug. In conclusion, we believe that physicians should carefully consider the risk of drug-induced hepatic injury when clopidogrel is prescribed.

Original language	English
Pages (from-to)	e8-e13
Journal	American Journal of Therapeutics
Volume	22
Issue number	1
DOIs	https://doi.org/10.1097/MJT.0b013e318293b0d6
Publication status	Published - Jan 21 2015

Keywords

clopidogrel
Drug-induced hepatotoxicity
liver biopsy
medical history

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Medicine(all)

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10.1097/MJT.0b013e318293b0d6

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Acute hepatitis associated with clopidogrel : A case report and review of the literature. / Pisapia, Raffaella; Abdeddaim, Amina ; Mariano, Andrea ; Rianda, Alessia ; Vincenzi, Laura; Taibi, Chiara; Baiocchini, Andrea; Del Nonno, Franca ; D'Offizi, Gianpiero.

In: American Journal of Therapeutics, Vol. 22, No. 1, 21.01.2015, p. e8-e13.

Research output: Contribution to journal › Article › peer-review

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abstract = "Drug-induced hepatotoxicity is a common cause of acute hepatitis, and the recognition of the responsible drug may be difficult. We describe a case of clopidogrel-related acute hepatitis. The diagnosis is strongly suggested by an accurate medical history and liver biopsy. Reports about cases of hepatotoxicity due to clopidogrel are increasing in the last few years, after the increased use of this drug. In conclusion, we believe that physicians should carefully consider the risk of drug-induced hepatic injury when clopidogrel is prescribed.",

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AU - Pisapia, Raffaella

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AU - Rianda, Alessia

AU - Vincenzi, Laura

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AU - Baiocchini, Andrea

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AU - D'Offizi, Gianpiero

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AB - Drug-induced hepatotoxicity is a common cause of acute hepatitis, and the recognition of the responsible drug may be difficult. We describe a case of clopidogrel-related acute hepatitis. The diagnosis is strongly suggested by an accurate medical history and liver biopsy. Reports about cases of hepatotoxicity due to clopidogrel are increasing in the last few years, after the increased use of this drug. In conclusion, we believe that physicians should carefully consider the risk of drug-induced hepatic injury when clopidogrel is prescribed.

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Acute hepatitis associated with clopidogrel: A case report and review of the literature

Abstract

Keywords

ASJC Scopus subject areas

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