Acute hypothalamic stimulation and ongoing cluster headache attacks

M. Leone, A. Franzini, G. Broggi, E. Mea, A. Proietti Cecchini, G. Bussone

Research output: Contribution to journalArticlepeer-review


Long-term hypothalamic stimulation is effective in improving drug-resistant chronic cluster headache (CH). We assessed acute hypothalamic stimulation to resolve ongoing CH attacks in 16 patients implanted to prevent chronic CH, investigating 136 attacks. A pain intensity reduction of ≥50% occurred in 25 of 108 evaluable attacks (23.1%). Acute hypothalamic stimulation is not effective in resolving ongoing CH attacks, suggesting that hypothalamic stimulation acts by complex mechanisms in CH prevention.

Original languageEnglish
Pages (from-to)1844-1845
Number of pages2
Issue number10
Publication statusPublished - Nov 2006

ASJC Scopus subject areas

  • Neuroscience(all)


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