Acute immune-mediated thrombocytopenia due to oxaliplatin administration: A case report

Filippo Pietrantonio; Maria Di Bartolomeo; Roberto Buzzoni; Emilio Bajetta

doi:10.1700/479.5667

Acute immune-mediated thrombocytopenia due to oxaliplatin administration: A case report

Filippo Pietrantonio, Maria Di Bartolomeo, Roberto Buzzoni, Emilio Bajetta

Fondazione IRCCS Istituto Nazionale dei Tumori

Research output: Contribution to journal › Article › peer-review

Abstract

Drug-induced acute thrombocytopenia is an extremely rare side effect that may occur immediately after oxaliplatin infusion. This potentially fatal reaction is immune mediated and can be anticipated by mild hemorrhagic signs during previous administrations. This is the first report of acute thrombocytopenia occurring during adjuvant treatment of colorectal cancer with oxaliplatin. Clinicians should be aware of this adverse event in order to prevent possible serious consequences and stop further oxaliplatin administration. Free full text available at www.tumorionline.it.

Original language	English
Pages (from-to)	154-156
Number of pages	3
Journal	Tumori
Volume	96
Issue number	1
DOIs	https://doi.org/10.1700/479.5667
Publication status	Published - Jan 2010

Keywords

Colorectal cancer
Hrombocytopenia
Oxaliplatin

ASJC Scopus subject areas

Cancer Research
Oncology

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abstract = "Drug-induced acute thrombocytopenia is an extremely rare side effect that may occur immediately after oxaliplatin infusion. This potentially fatal reaction is immune mediated and can be anticipated by mild hemorrhagic signs during previous administrations. This is the first report of acute thrombocytopenia occurring during adjuvant treatment of colorectal cancer with oxaliplatin. Clinicians should be aware of this adverse event in order to prevent possible serious consequences and stop further oxaliplatin administration. Free full text available at www.tumorionline.it.",

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AU - Buzzoni, Roberto

AU - Bajetta, Emilio

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AB - Drug-induced acute thrombocytopenia is an extremely rare side effect that may occur immediately after oxaliplatin infusion. This potentially fatal reaction is immune mediated and can be anticipated by mild hemorrhagic signs during previous administrations. This is the first report of acute thrombocytopenia occurring during adjuvant treatment of colorectal cancer with oxaliplatin. Clinicians should be aware of this adverse event in order to prevent possible serious consequences and stop further oxaliplatin administration. Free full text available at www.tumorionline.it.

KW - Colorectal cancer

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Acute immune-mediated thrombocytopenia due to oxaliplatin administration: A case report

Abstract

Keywords

ASJC Scopus subject areas

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