Acute infection with parvovirus B19 manifesting as brain stem encephalitis

Maria V. Moretti; Isabella Abbate; Maria R. Sciarrone; Giorgio Guercini; Daniela Francisci; Gian P. Pelliccioli; Franco Baldelli

Acute infection with parvovirus B19 manifesting as brain stem encephalitis

Maria V. Moretti, Isabella Abbate, Maria R. Sciarrone, Giorgio Guercini, Daniela Francisci, Gian P. Pelliccioli, Franco Baldelli

Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani

Research output: Contribution to journal › Article › peer-review

Abstract

Diseases associated with Parvovirus B19 infection are well known in pediatrics, obstetrics, and hematology, but the full clinical spectrum of these diseases has not yet been defined. We describe a patient with HIV infection and profound immunosuppression who subsequently developed brain stem encephalitis (rhombencephalitis) and transfusion-dependent anemia as a consequence of Parvovirus B19 infection. To our knowledge, this is the first reported case in which neurological manifestations coincided with evidence of acute infection with Parvovirus B19.

Original language	English
Pages (from-to)	173-179
Number of pages	7
Journal	Infections in Medicine
Volume	25
Issue number	4
Publication status	Published - Apr 2008

Keywords

AIDS
Encephalitis
HIV
Parvovirus B19

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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title = "Acute infection with parvovirus B19 manifesting as brain stem encephalitis",

abstract = "Diseases associated with Parvovirus B19 infection are well known in pediatrics, obstetrics, and hematology, but the full clinical spectrum of these diseases has not yet been defined. We describe a patient with HIV infection and profound immunosuppression who subsequently developed brain stem encephalitis (rhombencephalitis) and transfusion-dependent anemia as a consequence of Parvovirus B19 infection. To our knowledge, this is the first reported case in which neurological manifestations coincided with evidence of acute infection with Parvovirus B19.",

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AU - Moretti, Maria V.

AU - Abbate, Isabella

AU - Sciarrone, Maria R.

AU - Guercini, Giorgio

AU - Francisci, Daniela

AU - Pelliccioli, Gian P.

AU - Baldelli, Franco

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N2 - Diseases associated with Parvovirus B19 infection are well known in pediatrics, obstetrics, and hematology, but the full clinical spectrum of these diseases has not yet been defined. We describe a patient with HIV infection and profound immunosuppression who subsequently developed brain stem encephalitis (rhombencephalitis) and transfusion-dependent anemia as a consequence of Parvovirus B19 infection. To our knowledge, this is the first reported case in which neurological manifestations coincided with evidence of acute infection with Parvovirus B19.

AB - Diseases associated with Parvovirus B19 infection are well known in pediatrics, obstetrics, and hematology, but the full clinical spectrum of these diseases has not yet been defined. We describe a patient with HIV infection and profound immunosuppression who subsequently developed brain stem encephalitis (rhombencephalitis) and transfusion-dependent anemia as a consequence of Parvovirus B19 infection. To our knowledge, this is the first reported case in which neurological manifestations coincided with evidence of acute infection with Parvovirus B19.

KW - AIDS

KW - Encephalitis

KW - HIV

KW - Parvovirus B19

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