Acute juvenile cataract in newly diagnosed type 1 diabetic patients: A description of six cases

Dario Iafusco, Francesco Prisco, Mario R. Romano, Roberto Dell'Omo, Teodosio Libondi, Ciro Costagliola

Research output: Contribution to journalArticlepeer-review

Abstract

Cataract represents one of the most frequent eye complications in type 1 and type 2 patients; contrarily, acute cataract in young diabetic patients occurs very rarely. The aim of this study was to describe six cases of acute cataract in adolescents at the onset of type 1 diabetes. Eight hundred and twenty-six patients with type 1 diabetes were retrospectively studied. A multivariate analysis was applied to verify the weight of the following laboratory findings taken on admission (independent variables): glycemia, glycated hemoglobin (HbA1c), pH, base excess (BE),and on the occurrence of cataract (dependent variable). Six patients (0.7%) presented with acute lens opacities. Cataract development was significantly correlated with HbA1c and glycemia. The relative risk increases about twice for each percentage point from 12.8 to 14.1% of HbA1c; glycemic blood levels represent a moderate risk factor for cataractogenesis. Ketoacidosis and BE were not significantly correlated.

Original languageEnglish
Pages (from-to)642-648
Number of pages7
JournalPediatric Diabetes
Volume12
Issue number7
DOIs
Publication statusPublished - Nov 2011

Keywords

  • Cataract
  • Juvenile diabetes
  • Lens

ASJC Scopus subject areas

  • Internal Medicine
  • Pediatrics, Perinatology, and Child Health
  • Endocrinology, Diabetes and Metabolism

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