Acute kidney injury

Classification and staging

Dinna N. Cruz, Sean M. Bagshaw, Claudio Ronco, Zaccaria Ricci

Research output: Chapter in Book/Report/Conference proceedingChapter

24 Citations (Scopus)

Abstract

It was not until recently that consensus definitions for acute kidney injury (AKI) were proposed and published. The RIFLE (Risk-Injury-Failure-Loss- End-stage renal disease) and AKIN (Acute Kidney Injury Network) classifications were designed in order to be easily understood and applied in a variety of clinical and research settings. Their creation was intended to uniformly establish the presence or absence of the AKI and to give a quantitative idea of the severity of the disease unifying the commonly used parameters of serum creatinine and urine output. Subsequent validation showed that both the presence and severity of AKI, defined using RIFLE/AKIN, correlate well with patient outcome. This review will briefly describe the RIFLE/AKIN consensus definitions, its subsequent revisions and its successful validation and application to clinical research. The potential of extending the use of RIFLE/AKIN to the clinical setting of cardiorenal syndromes is also discussed.

Original languageEnglish
Title of host publicationContributions to Nephrology
Pages24-32
Number of pages9
Volume164
DOIs
Publication statusPublished - Apr 2010

Publication series

NameContributions to Nephrology
Volume164
ISSN (Print)03025144

Fingerprint

Acute Kidney Injury
Cardio-Renal Syndrome
Research
Chronic Kidney Failure
Creatinine
Urine
Wounds and Injuries
Serum

ASJC Scopus subject areas

  • Nephrology

Cite this

Cruz, D. N., Bagshaw, S. M., Ronco, C., & Ricci, Z. (2010). Acute kidney injury: Classification and staging. In Contributions to Nephrology (Vol. 164, pp. 24-32). (Contributions to Nephrology; Vol. 164). https://doi.org/10.1159/000313717

Acute kidney injury : Classification and staging. / Cruz, Dinna N.; Bagshaw, Sean M.; Ronco, Claudio; Ricci, Zaccaria.

Contributions to Nephrology. Vol. 164 2010. p. 24-32 (Contributions to Nephrology; Vol. 164).

Research output: Chapter in Book/Report/Conference proceedingChapter

Cruz, DN, Bagshaw, SM, Ronco, C & Ricci, Z 2010, Acute kidney injury: Classification and staging. in Contributions to Nephrology. vol. 164, Contributions to Nephrology, vol. 164, pp. 24-32. https://doi.org/10.1159/000313717
Cruz DN, Bagshaw SM, Ronco C, Ricci Z. Acute kidney injury: Classification and staging. In Contributions to Nephrology. Vol. 164. 2010. p. 24-32. (Contributions to Nephrology). https://doi.org/10.1159/000313717
Cruz, Dinna N. ; Bagshaw, Sean M. ; Ronco, Claudio ; Ricci, Zaccaria. / Acute kidney injury : Classification and staging. Contributions to Nephrology. Vol. 164 2010. pp. 24-32 (Contributions to Nephrology).
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