Abstract
We retrospectively reviewed the databases of seven studies on acute lymphoblastic leukemia (ALL) by the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) to identify patients with associated genetic disease, other than Down's syndrome. Forty-two patients were reported to have associated genetic conditions that included β-thalassemia (n=10), ataxia- telangiectasia (n=5), neurofibromatosis (n=3), Sotos syndrome (n=2) and other individual conditions. Patients with ataxia-telangiectasia, all with T-cell ALL, had a higher frequency of adverse events.
| Original language | English |
|---|---|
| Pages (from-to) | 139-140 |
| Number of pages | 2 |
| Journal | Haematologica |
| Volume | 91 |
| Issue number | 1 |
| Publication status | Published - Jan 2006 |
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Keywords
- Acute lymphoblastic leukemia
- Genetic diseases
- Malformation
ASJC Scopus subject areas
- Hematology
Cite this
Acute lymphoblastic leukemia in children with associated genetic conditions other than Down's syndrome. The AIEOP experience. / Ziino, Ottavio; Rondelli, Roberta; Micalizzi, Concetta; Luciani, Matteo; Conter, Valentino; Aricò, Maurizio.
In: Haematologica, Vol. 91, No. 1, 01.2006, p. 139-140.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Acute lymphoblastic leukemia in children with associated genetic conditions other than Down's syndrome. The AIEOP experience
AU - Ziino, Ottavio
AU - Rondelli, Roberta
AU - Micalizzi, Concetta
AU - Luciani, Matteo
AU - Conter, Valentino
AU - Aricò, Maurizio
PY - 2006/1
Y1 - 2006/1
N2 - We retrospectively reviewed the databases of seven studies on acute lymphoblastic leukemia (ALL) by the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) to identify patients with associated genetic disease, other than Down's syndrome. Forty-two patients were reported to have associated genetic conditions that included β-thalassemia (n=10), ataxia- telangiectasia (n=5), neurofibromatosis (n=3), Sotos syndrome (n=2) and other individual conditions. Patients with ataxia-telangiectasia, all with T-cell ALL, had a higher frequency of adverse events.
AB - We retrospectively reviewed the databases of seven studies on acute lymphoblastic leukemia (ALL) by the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) to identify patients with associated genetic disease, other than Down's syndrome. Forty-two patients were reported to have associated genetic conditions that included β-thalassemia (n=10), ataxia- telangiectasia (n=5), neurofibromatosis (n=3), Sotos syndrome (n=2) and other individual conditions. Patients with ataxia-telangiectasia, all with T-cell ALL, had a higher frequency of adverse events.
KW - Acute lymphoblastic leukemia
KW - Genetic diseases
KW - Malformation
UR - http://www.scopus.com/inward/record.url?scp=32544445872&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=32544445872&partnerID=8YFLogxK
M3 - Article
VL - 91
SP - 139
EP - 140
JO - Haematologica
JF - Haematologica
SN - 0390-6078
IS - 1
ER -