Acute lymphoblastic leukemia in children with associated genetic conditions other than Down's syndrome. The AIEOP experience

Ottavio Ziino, Roberta Rondelli, Concetta Micalizzi, Matteo Luciani, Valentino Conter, Maurizio Aricò

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

We retrospectively reviewed the databases of seven studies on acute lymphoblastic leukemia (ALL) by the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) to identify patients with associated genetic disease, other than Down's syndrome. Forty-two patients were reported to have associated genetic conditions that included β-thalassemia (n=10), ataxia- telangiectasia (n=5), neurofibromatosis (n=3), Sotos syndrome (n=2) and other individual conditions. Patients with ataxia-telangiectasia, all with T-cell ALL, had a higher frequency of adverse events.

Original languageEnglish
Pages (from-to)139-140
Number of pages2
JournalHaematologica
Volume91
Issue number1
Publication statusPublished - Jan 2006

Fingerprint

Down Syndrome
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Ataxia Telangiectasia
Sotos Syndrome
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Inborn Genetic Diseases
Neurofibromatoses
Thalassemia
Databases

Keywords

  • Acute lymphoblastic leukemia
  • Genetic diseases
  • Malformation

ASJC Scopus subject areas

  • Hematology

Cite this

Acute lymphoblastic leukemia in children with associated genetic conditions other than Down's syndrome. The AIEOP experience. / Ziino, Ottavio; Rondelli, Roberta; Micalizzi, Concetta; Luciani, Matteo; Conter, Valentino; Aricò, Maurizio.

In: Haematologica, Vol. 91, No. 1, 01.2006, p. 139-140.

Research output: Contribution to journalArticle

Ziino, Ottavio ; Rondelli, Roberta ; Micalizzi, Concetta ; Luciani, Matteo ; Conter, Valentino ; Aricò, Maurizio. / Acute lymphoblastic leukemia in children with associated genetic conditions other than Down's syndrome. The AIEOP experience. In: Haematologica. 2006 ; Vol. 91, No. 1. pp. 139-140.
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