Abstract
A terminal deletion of the long arm of one chromosome 21 at band q21 was found in two patients with acute leukemia and a low platelet count: one case of acute myelomonocytic leukemia and one case of acute lymphocytic leukemia. The segment deleted from chromosome 21 could not be found translocated to any other chromosome of the complement. The results indicate that the 21q- marker chromosome may be due to a true deletion and that the marker is not specific for primary thrombocythemia or other myeloproliferative disorders associated with thrombocytosis.
Original language | English |
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Pages (from-to) | 329-331 |
Number of pages | 3 |
Journal | Human Genetics |
Volume | 57 |
Issue number | 3 |
DOIs | |
Publication status | Published - May 1981 |
ASJC Scopus subject areas
- Genetics(clinical)
- Genetics