Acute myelitis as presenting symptom of HIV-HTLV-1 co-infection

Alberto Cucca, L. Stragapede, Lucia Antonutti, Mauro Catalan, Ilaria Caracciolo, Romina Valentinotti, A. Granato, Pierlanfranco D'Agaro

Research output: Contribution to journalArticle

Abstract

A 21-year-old woman presented with acute-onset spastic paraparesis. The MRI spinal scan revealed a contrast-enhanced T2 hyperintensity between C5–T2. The most common neurotropic pathogens were excluded by first level tests. Under suspicion of an acute immune-mediated myelitis, a corticosteroid therapy was administered. However, a seropositivity for both human immunodeficiency virus (HIV) type 1 and human T-lymphotropic virus (HTLV) subsequently emerged. An antiretroviral therapy was started while steroids discontinued. Patient’s clinical conditions remained unchanged. HIV-HTLV-1 co-infection should be included in the differential diagnosis of any acute myelitis, even in patients with a preserved immune status and no risk factors.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalJournal of NeuroVirology
DOIs
Publication statusAccepted/In press - May 31 2016

Keywords

  • HIV
  • HTLV
  • Myelitis

ASJC Scopus subject areas

  • Virology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Neurology

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    Cucca, A., Stragapede, L., Antonutti, L., Catalan, M., Caracciolo, I., Valentinotti, R., Granato, A., & D'Agaro, P. (Accepted/In press). Acute myelitis as presenting symptom of HIV-HTLV-1 co-infection. Journal of NeuroVirology, 1-5. https://doi.org/10.1007/s13365-016-0455-2