Acute myocarditis and left ventricular aneurysm as presentations of systemic lupus erythematosus

Andrea Frustaci, Nicola Gentiloni, Marina Caldarulo

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

A case of systemic lupus erythematosus (SLE) associated with fever, heart failure, and left ventricular (LV) aneurysm is reported. A diagnosis of SLE was suspected owing to the presence of active lymphocytic myocarditis and fibrinous endocarditis at LV endomyocardial biopsy and was confirmed by identification of 4 of the 11 criteria proposed by the American Rheumatism Association for the definition of SLE. A 2-month period of steroid therapy was followed by a remarkable recovery of LV function and progression of endomyocarditis to a healed phase at control LV biopsy. The LV aneurysm disappeared, likely because thrombosis occurred as a result of the hypercoagulable state accompanying the presence of anticardiolipin antibodies. This is the first reported case of LV aneurysm induced by SLE and is a rare clinicohistologic documentation of the effectiveness of steroid treatment on lupus endomyocarditis.

Original languageEnglish
Pages (from-to)282-284
Number of pages3
JournalChest
Volume109
Issue number1
Publication statusPublished - 1996

Fingerprint

Myocarditis
Systemic Lupus Erythematosus
Aneurysm
Steroids
Biopsy
Anticardiolipin Antibodies
Endocarditis
Rheumatic Diseases
Left Ventricular Function
Documentation
Thrombosis
Fever
Heart Failure
Therapeutics

Keywords

  • cardiac aneurysm
  • endomyocarditis
  • systemic lupus erythematosus

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Acute myocarditis and left ventricular aneurysm as presentations of systemic lupus erythematosus. / Frustaci, Andrea; Gentiloni, Nicola; Caldarulo, Marina.

In: Chest, Vol. 109, No. 1, 1996, p. 282-284.

Research output: Contribution to journalArticle

Frustaci, Andrea ; Gentiloni, Nicola ; Caldarulo, Marina. / Acute myocarditis and left ventricular aneurysm as presentations of systemic lupus erythematosus. In: Chest. 1996 ; Vol. 109, No. 1. pp. 282-284.
@article{75f6a65170de4687920c947ef70a7a6a,
title = "Acute myocarditis and left ventricular aneurysm as presentations of systemic lupus erythematosus",
abstract = "A case of systemic lupus erythematosus (SLE) associated with fever, heart failure, and left ventricular (LV) aneurysm is reported. A diagnosis of SLE was suspected owing to the presence of active lymphocytic myocarditis and fibrinous endocarditis at LV endomyocardial biopsy and was confirmed by identification of 4 of the 11 criteria proposed by the American Rheumatism Association for the definition of SLE. A 2-month period of steroid therapy was followed by a remarkable recovery of LV function and progression of endomyocarditis to a healed phase at control LV biopsy. The LV aneurysm disappeared, likely because thrombosis occurred as a result of the hypercoagulable state accompanying the presence of anticardiolipin antibodies. This is the first reported case of LV aneurysm induced by SLE and is a rare clinicohistologic documentation of the effectiveness of steroid treatment on lupus endomyocarditis.",
keywords = "cardiac aneurysm, endomyocarditis, systemic lupus erythematosus",
author = "Andrea Frustaci and Nicola Gentiloni and Marina Caldarulo",
year = "1996",
language = "English",
volume = "109",
pages = "282--284",
journal = "Chest",
issn = "0012-3692",
publisher = "Elsevier Inc.",
number = "1",

}

TY - JOUR

T1 - Acute myocarditis and left ventricular aneurysm as presentations of systemic lupus erythematosus

AU - Frustaci, Andrea

AU - Gentiloni, Nicola

AU - Caldarulo, Marina

PY - 1996

Y1 - 1996

N2 - A case of systemic lupus erythematosus (SLE) associated with fever, heart failure, and left ventricular (LV) aneurysm is reported. A diagnosis of SLE was suspected owing to the presence of active lymphocytic myocarditis and fibrinous endocarditis at LV endomyocardial biopsy and was confirmed by identification of 4 of the 11 criteria proposed by the American Rheumatism Association for the definition of SLE. A 2-month period of steroid therapy was followed by a remarkable recovery of LV function and progression of endomyocarditis to a healed phase at control LV biopsy. The LV aneurysm disappeared, likely because thrombosis occurred as a result of the hypercoagulable state accompanying the presence of anticardiolipin antibodies. This is the first reported case of LV aneurysm induced by SLE and is a rare clinicohistologic documentation of the effectiveness of steroid treatment on lupus endomyocarditis.

AB - A case of systemic lupus erythematosus (SLE) associated with fever, heart failure, and left ventricular (LV) aneurysm is reported. A diagnosis of SLE was suspected owing to the presence of active lymphocytic myocarditis and fibrinous endocarditis at LV endomyocardial biopsy and was confirmed by identification of 4 of the 11 criteria proposed by the American Rheumatism Association for the definition of SLE. A 2-month period of steroid therapy was followed by a remarkable recovery of LV function and progression of endomyocarditis to a healed phase at control LV biopsy. The LV aneurysm disappeared, likely because thrombosis occurred as a result of the hypercoagulable state accompanying the presence of anticardiolipin antibodies. This is the first reported case of LV aneurysm induced by SLE and is a rare clinicohistologic documentation of the effectiveness of steroid treatment on lupus endomyocarditis.

KW - cardiac aneurysm

KW - endomyocarditis

KW - systemic lupus erythematosus

UR - http://www.scopus.com/inward/record.url?scp=0030029303&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030029303&partnerID=8YFLogxK

M3 - Article

C2 - 8549201

AN - SCOPUS:0030029303

VL - 109

SP - 282

EP - 284

JO - Chest

JF - Chest

SN - 0012-3692

IS - 1

ER -