Abstract
A case of systemic lupus erythematosus (SLE) associated with fever, heart failure, and left ventricular (LV) aneurysm is reported. A diagnosis of SLE was suspected owing to the presence of active lymphocytic myocarditis and fibrinous endocarditis at LV endomyocardial biopsy and was confirmed by identification of 4 of the 11 criteria proposed by the American Rheumatism Association for the definition of SLE. A 2-month period of steroid therapy was followed by a remarkable recovery of LV function and progression of endomyocarditis to a healed phase at control LV biopsy. The LV aneurysm disappeared, likely because thrombosis occurred as a result of the hypercoagulable state accompanying the presence of anticardiolipin antibodies. This is the first reported case of LV aneurysm induced by SLE and is a rare clinicohistologic documentation of the effectiveness of steroid treatment on lupus endomyocarditis.
| Original language | English |
|---|---|
| Pages (from-to) | 282-284 |
| Number of pages | 3 |
| Journal | Chest |
| Volume | 109 |
| Issue number | 1 |
| Publication status | Published - 1996 |
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Keywords
- cardiac aneurysm
- endomyocarditis
- systemic lupus erythematosus
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
Cite this
Acute myocarditis and left ventricular aneurysm as presentations of systemic lupus erythematosus. / Frustaci, Andrea; Gentiloni, Nicola; Caldarulo, Marina.
In: Chest, Vol. 109, No. 1, 1996, p. 282-284.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Acute myocarditis and left ventricular aneurysm as presentations of systemic lupus erythematosus
AU - Frustaci, Andrea
AU - Gentiloni, Nicola
AU - Caldarulo, Marina
PY - 1996
Y1 - 1996
N2 - A case of systemic lupus erythematosus (SLE) associated with fever, heart failure, and left ventricular (LV) aneurysm is reported. A diagnosis of SLE was suspected owing to the presence of active lymphocytic myocarditis and fibrinous endocarditis at LV endomyocardial biopsy and was confirmed by identification of 4 of the 11 criteria proposed by the American Rheumatism Association for the definition of SLE. A 2-month period of steroid therapy was followed by a remarkable recovery of LV function and progression of endomyocarditis to a healed phase at control LV biopsy. The LV aneurysm disappeared, likely because thrombosis occurred as a result of the hypercoagulable state accompanying the presence of anticardiolipin antibodies. This is the first reported case of LV aneurysm induced by SLE and is a rare clinicohistologic documentation of the effectiveness of steroid treatment on lupus endomyocarditis.
AB - A case of systemic lupus erythematosus (SLE) associated with fever, heart failure, and left ventricular (LV) aneurysm is reported. A diagnosis of SLE was suspected owing to the presence of active lymphocytic myocarditis and fibrinous endocarditis at LV endomyocardial biopsy and was confirmed by identification of 4 of the 11 criteria proposed by the American Rheumatism Association for the definition of SLE. A 2-month period of steroid therapy was followed by a remarkable recovery of LV function and progression of endomyocarditis to a healed phase at control LV biopsy. The LV aneurysm disappeared, likely because thrombosis occurred as a result of the hypercoagulable state accompanying the presence of anticardiolipin antibodies. This is the first reported case of LV aneurysm induced by SLE and is a rare clinicohistologic documentation of the effectiveness of steroid treatment on lupus endomyocarditis.
KW - cardiac aneurysm
KW - endomyocarditis
KW - systemic lupus erythematosus
UR - http://www.scopus.com/inward/record.url?scp=0030029303&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030029303&partnerID=8YFLogxK
M3 - Article
C2 - 8549201
AN - SCOPUS:0030029303
VL - 109
SP - 282
EP - 284
JO - Chest
JF - Chest
SN - 0012-3692
IS - 1
ER -