Acute onset of bulbar amyotrophic lateral sclerosis after flu - look at the differential diagnosis: A case report

Simona Portaro, Teresa Brizzi, Antonino Naro, Valeria Conti Nibali, Rosa Morabito, Alessia Bramanti, Rocco Salvatore Calabrò

Research output: Contribution to journalArticle

Abstract

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder affecting upper and lower motor neurones. It can be either familial (fALS) or sporadic (sALS). ALS is characterized by muscle weakness and atrophy that can involve the limbs and trunk (i.e. the spinal form of the disease) or speech and swallowing (i.e. the bulbar form). The aetiology of sALS remains unclear although a gene-environment interaction has been proposed as a concomitant trigger for the neurodegenerative process together with viral infections, smoking, heavy metals and pesticide exposure. Herein, we report the case of a 67-year-old woman who experienced an acute onset of bulbar ALS with an atypical clinical course that was probably triggered by a bout of influenza.

Original languageEnglish
Pages (from-to)2933-2937
Number of pages5
JournalJournal of International Medical Research
Volume46
Issue number7
DOIs
Publication statusPublished - Jul 2018

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Amyotrophic Lateral Sclerosis
Heavy Metals
Pesticides
Neurons
Muscle
Differential Diagnosis
Genes
Spinal Diseases
Gene-Environment Interaction
Muscular Atrophy
Muscle Weakness
Motor Neurons
Virus Diseases
Deglutition
Neurodegenerative Diseases
Human Influenza
Extremities
Smoking

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Acute onset of bulbar amyotrophic lateral sclerosis after flu - look at the differential diagnosis : A case report. / Portaro, Simona; Brizzi, Teresa; Naro, Antonino; Conti Nibali, Valeria; Morabito, Rosa; Bramanti, Alessia; Calabrò, Rocco Salvatore.

In: Journal of International Medical Research, Vol. 46, No. 7, 07.2018, p. 2933-2937.

Research output: Contribution to journalArticle

Portaro, Simona ; Brizzi, Teresa ; Naro, Antonino ; Conti Nibali, Valeria ; Morabito, Rosa ; Bramanti, Alessia ; Calabrò, Rocco Salvatore. / Acute onset of bulbar amyotrophic lateral sclerosis after flu - look at the differential diagnosis : A case report. In: Journal of International Medical Research. 2018 ; Vol. 46, No. 7. pp. 2933-2937.
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