Acute pancreatitis associated with primary hyperparathyroidism

Alberto Biondi, Roberto Persiani, Michele Marchese, Ferdinando Cananzi, Domenico D'Ugo

Research output: Contribution to journalArticlepeer-review


Coexistence of primary hyperparathyroidism and acute pancreatitis has widely been reported in literature, but a causal relationship remains controversial. A case of acute pancreatitis as a first symptom of primary hyperparathyroidism with severe hypercalcemia is reported. In this patient a reduction of serum calcium level was obtained with medical therapy and resulted in the resolution of acute pancreatitis symptoms within 10 days. At the same time a parathyroid adenoma was clinically identified and elective parathyroidectomy was performed with complete normalization of intact parathyroid hormone and serum calcium level. At three-year follow-up, no recurrence or complications of pancreatitis were documented. The presented case suggests a cause and effect relationship between acute pancreatitis and severe hypercalcemia which should be kept in mind in the differential diagnosis of nonbiliary, non-alcoholic acute pancreatitis. Reduction of hypercalcemia with medical treatment can represent a good chance for elective surgical neck exploration.

Original languageEnglish
Pages (from-to)135-138
Number of pages4
JournalUpdates in Surgery
Issue number2
Publication statusPublished - 2011


  • Acute pancreatitis
  • Hypercalcemia
  • Primary hyperparathyroidism

ASJC Scopus subject areas

  • Surgery


Dive into the research topics of 'Acute pancreatitis associated with primary hyperparathyroidism'. Together they form a unique fingerprint.

Cite this