Acute pancreatitis during oral 5-aminosalicylic acid therapy

M. T. Fiorentini, M. Fracchia, G. Galatola, A. Barlotta, M. De La Pierre

Research output: Contribution to journalArticle

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Abstract

Therapy with oral 5-aminosalicylic acid for inflammatory bowel disease has been reported as effective and safe. We report two cases of biochemically proven mild acute pancreatitis occurring 2 and 14 days, respectively, after oral 5-aminosalicylic acid therapy was instituted for inflammatory bowel disease. A hypersensitivity mechanism might be involved, owing to possible erratic systemic absorption of the drug. We suggest clinical and biochemical monitoring for patients undergoing oral 5-aminosalicylic acid therapy in order to confirm its possible association with acute pancreatitis and to assess the actual incidence of such an adverse reaction.

Original languageEnglish
Pages (from-to)1180-1182
Number of pages3
JournalDigestive Diseases and Sciences
Volume35
Issue number9
DOIs
Publication statusPublished - Sep 1990

Fingerprint

Mesalamine
Pancreatitis
Inflammatory Bowel Diseases
Physiologic Monitoring
Hypersensitivity
Therapeutics
Incidence
Pharmaceutical Preparations

Keywords

  • 5-aminosalicylic acid
  • acute pancreatitis
  • drug adverse reactions
  • inflammatory bowel disease

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Fiorentini, M. T., Fracchia, M., Galatola, G., Barlotta, A., & De La Pierre, M. (1990). Acute pancreatitis during oral 5-aminosalicylic acid therapy. Digestive Diseases and Sciences, 35(9), 1180-1182. https://doi.org/10.1007/BF01537594

Acute pancreatitis during oral 5-aminosalicylic acid therapy. / Fiorentini, M. T.; Fracchia, M.; Galatola, G.; Barlotta, A.; De La Pierre, M.

In: Digestive Diseases and Sciences, Vol. 35, No. 9, 09.1990, p. 1180-1182.

Research output: Contribution to journalArticle

Fiorentini, MT, Fracchia, M, Galatola, G, Barlotta, A & De La Pierre, M 1990, 'Acute pancreatitis during oral 5-aminosalicylic acid therapy', Digestive Diseases and Sciences, vol. 35, no. 9, pp. 1180-1182. https://doi.org/10.1007/BF01537594
Fiorentini, M. T. ; Fracchia, M. ; Galatola, G. ; Barlotta, A. ; De La Pierre, M. / Acute pancreatitis during oral 5-aminosalicylic acid therapy. In: Digestive Diseases and Sciences. 1990 ; Vol. 35, No. 9. pp. 1180-1182.
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