Abstract
Purpose: To report a case of Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE) in the course of Ulcerative Colitis (UC). Methods: A complete ophthalmologic evaluation, including fluorescein and indocyanine green angiography, was performed. Results: A patient with exacerbation of UC was referred to our department for sudden visual loss in RE. Ophthalmoscopy disclosed multifocal yellow-white placoid lesions typical of APMPPE in RE. There were no lesions in the fellow eye. On fluorescein angiography (FA), the active lesions showed early hypofluorescence, followed by late staining. Indocyanine green angiography (ICGA) revealed early and late hypofluorescence corresponding to the lesions observed clinically, and late anular staining surrounding a hypofluorescent lesion at the posterior pole. On LE ICGA revealed lesions not detected with ophthalmoscopy and FA. After corticosteroid therapy the lesions healed. Conclusion: Ulcerative Colitis may be responsible for the onset of AMPPPE by an immunological mechanism of delayed type hypersensitivity reaction.
| Original language | English |
|---|---|
| Pages (from-to) | 319-321 |
| Number of pages | 3 |
| Journal | Acta Ophthalmologica Scandinavica |
| Volume | 79 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2001 |
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Keywords
- Acute posterior multifocal placoid pigment epitheliopathy(APMPPE)
- Ulcerative colitis (UC)
ASJC Scopus subject areas
- Ophthalmology
Cite this
Acute posterior multifocal placoid pigment epitheliopathy and ulcerative colitis : A possible association. / Di Crecchio, Lorenzo; Parodi, Maurizio Battaglia; Saviano, Sandro; Ravalico, Giuseppe.
In: Acta Ophthalmologica Scandinavica, Vol. 79, No. 3, 2001, p. 319-321.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Acute posterior multifocal placoid pigment epitheliopathy and ulcerative colitis
T2 - A possible association
AU - Di Crecchio, Lorenzo
AU - Parodi, Maurizio Battaglia
AU - Saviano, Sandro
AU - Ravalico, Giuseppe
PY - 2001
Y1 - 2001
N2 - Purpose: To report a case of Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE) in the course of Ulcerative Colitis (UC). Methods: A complete ophthalmologic evaluation, including fluorescein and indocyanine green angiography, was performed. Results: A patient with exacerbation of UC was referred to our department for sudden visual loss in RE. Ophthalmoscopy disclosed multifocal yellow-white placoid lesions typical of APMPPE in RE. There were no lesions in the fellow eye. On fluorescein angiography (FA), the active lesions showed early hypofluorescence, followed by late staining. Indocyanine green angiography (ICGA) revealed early and late hypofluorescence corresponding to the lesions observed clinically, and late anular staining surrounding a hypofluorescent lesion at the posterior pole. On LE ICGA revealed lesions not detected with ophthalmoscopy and FA. After corticosteroid therapy the lesions healed. Conclusion: Ulcerative Colitis may be responsible for the onset of AMPPPE by an immunological mechanism of delayed type hypersensitivity reaction.
AB - Purpose: To report a case of Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE) in the course of Ulcerative Colitis (UC). Methods: A complete ophthalmologic evaluation, including fluorescein and indocyanine green angiography, was performed. Results: A patient with exacerbation of UC was referred to our department for sudden visual loss in RE. Ophthalmoscopy disclosed multifocal yellow-white placoid lesions typical of APMPPE in RE. There were no lesions in the fellow eye. On fluorescein angiography (FA), the active lesions showed early hypofluorescence, followed by late staining. Indocyanine green angiography (ICGA) revealed early and late hypofluorescence corresponding to the lesions observed clinically, and late anular staining surrounding a hypofluorescent lesion at the posterior pole. On LE ICGA revealed lesions not detected with ophthalmoscopy and FA. After corticosteroid therapy the lesions healed. Conclusion: Ulcerative Colitis may be responsible for the onset of AMPPPE by an immunological mechanism of delayed type hypersensitivity reaction.
KW - Acute posterior multifocal placoid pigment epitheliopathy(APMPPE)
KW - Ulcerative colitis (UC)
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UR - http://www.scopus.com/inward/citedby.url?scp=0034972635&partnerID=8YFLogxK
U2 - 10.1034/j.1600-0420.2001.790324.x
DO - 10.1034/j.1600-0420.2001.790324.x
M3 - Article
C2 - 11401649
AN - SCOPUS:0034972635
VL - 79
SP - 319
EP - 321
JO - Acta Ophthalmologica Scandinavica
JF - Acta Ophthalmologica Scandinavica
SN - 1395-3907
IS - 3
ER -