Mediastinite acuta postoperatoria: analisi retrospettiva di differenti metodiche di trattamento.

Translated title of the contribution: Acute postoperative mediastinitis: retrospective analysis of various treatment methods

S. Lanzi, V. Borghetti, G. Pulcini, G. Coletti, P. Totaro, F. Biasca, F. Giampaoli, A. Pouché, G. Minzioni

Research output: Contribution to journalArticlepeer-review


Infective acute mediastinitis is a postoperative complication reported in 0.5-1% of patients undergoing open chest operations. The treatment of choice for this life-threatening complication is still a matter of debate. The aim of this study was to retrospectively analyse the efficacy of different therapeutic approaches in the treatment of postoperative infective mediastinitis. In the 2nd Division of Cardiac Surgery, from October 1986 to May 2000, 10,234 patients underwent cardiac surgery operations. In 42 patients (0.4%) the operation was complicated by acute infective mediastinitis requiring surgical treatment. On the basis of the treatment opted for, these patients were subdivided into 5 groups: 23 patients underwent continuous iodopovidone (Betadine) mediastinal irrigation (GL) associated with surgical omentoplasty in 8 patients (GLO); 5 patients underwent isolated omentoplasty (GO), and 4 patients were treated with a pectoral muscle flap (GF). In 8 patients other different procedures were performed (GS). There were no deaths in GF and GS despite 24% and 20% mortality reported among patients who underwent mediastinal irrigation (GL) and isolated omentoplasty (GO), respectively. The mean hospital stay was 15 +/- 1 days in GF, 16 +/- 1 days in GS, 25 +/- 11 in patients who underwent omentoplasty and 27 +/- 14 in patients who underwent mediastinal irrigation. Predictors of death were low cardiac output syndrome (P <or = 0.009) and respiratory insufficiency (P <or = 0.032) when found before treatment. Our study suggests that surgical omentoplasty should be the treatment of choice in deep mediastinal infections, whereas wound sterilisation, associated with surgical chest wall reconstruction, seems to be a better procedure in superficial infective disease. A more extended clinical series would be needed to confirm these preliminary data.

Translated title of the contributionAcute postoperative mediastinitis: retrospective analysis of various treatment methods
Original languageItalian
Pages (from-to)665-672
Number of pages8
JournalChirurgia Italiana
Issue number5
Publication statusPublished - Sep 2001

ASJC Scopus subject areas

  • Surgery


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