Acute pyelonephritis as a cause of hyponatremia/hyperkalemia in young infants with urinary tract malformations

Maria L. Melzi, Sophie Guez, Giovanna Sersale, Fabiola Terzi, Elena Secco, Giuseppina Marra, Amedea S. Tirelli, Baroukh M. Assael

Research output: Contribution to journalArticle

Abstract

Obstructive uropathy causes tubular resistance to aldosterone and severe metabolic imbalance may be precipitated by an episode of pyelonephritis. In the last 3 years we investigated 52 episodes of pyelonephritis (positive urine culture, elevated C reactive protein, fever, elevated neutrophil count) in 50 children between 15 days and 15 months of age. Ultrasonography voiding cystography and renal scintiscan were performed in all cases and iv urography in some.A salt-losing syndrome with hyponatremia and hyperkalemia (Na 6.3 meq/liter) was observed in 17 infants

Original languageEnglish
Pages (from-to)56-59
Number of pages4
JournalPediatric Infectious Disease Journal
Volume14
Issue number1
Publication statusPublished - 1995

Keywords

  • Aldosterone resistance
  • Hyperkalemia
  • Hyponatremia
  • Pyelonephritis
  • Urinary tract malformations

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)
  • Pediatrics, Perinatology, and Child Health

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