TY - JOUR
T1 - Acute renal failure after isolated CABG surgery
T2 - Six years of experience
AU - Landoni, Giovanni
AU - Bove, T.
AU - Crivellari, M.
AU - Poli, D.
AU - Fochi, O.
AU - Marchetti, C.
AU - Romano, A.
AU - Marino, G.
AU - Zangrillo, A.
PY - 2007/11
Y1 - 2007/11
N2 - Background. A prospective observational study was carried out in a Cardiosurgical Intensive Care Unit (ICU) in order to evaluate the incidence of Acute Renal Failure (ARF) after coronary artery bypass graft surgery and identify its predictors. The effects of ARF on outcome were also investigated. Methods. The study enrolled 3013 consecutive patients undergoing coronary artery bypass graft surgery. Baseline variables including age, sex, preoperative renal failure, left-ventricular dysfunction, emergency surgery, neurological adverse events, patient history of chronic obstructive pulmonary disease and diabetes mellitus were collected. Intraoperative variables were: type of surgery (on- or off-pump), intra-aortic balloon pump placement, and cardiopulmonary bypass duration. The measured postoperative variables were: low cardiac output syndrome, hemorrhage, transfusion of blood products, and surgical revision. Results. Preoperative renal dysfunction (creatinine > 1.4 mg/dL), blood transfusion, low-output syndrome, emergency surgery, low ejection fraction and age were independently associated with ARF. The median (interquartile range) ICU stay was 5.5 (range 4-11.5) days in patients who did and I (range 1-2) day in those who did not develop ARF (P
AB - Background. A prospective observational study was carried out in a Cardiosurgical Intensive Care Unit (ICU) in order to evaluate the incidence of Acute Renal Failure (ARF) after coronary artery bypass graft surgery and identify its predictors. The effects of ARF on outcome were also investigated. Methods. The study enrolled 3013 consecutive patients undergoing coronary artery bypass graft surgery. Baseline variables including age, sex, preoperative renal failure, left-ventricular dysfunction, emergency surgery, neurological adverse events, patient history of chronic obstructive pulmonary disease and diabetes mellitus were collected. Intraoperative variables were: type of surgery (on- or off-pump), intra-aortic balloon pump placement, and cardiopulmonary bypass duration. The measured postoperative variables were: low cardiac output syndrome, hemorrhage, transfusion of blood products, and surgical revision. Results. Preoperative renal dysfunction (creatinine > 1.4 mg/dL), blood transfusion, low-output syndrome, emergency surgery, low ejection fraction and age were independently associated with ARF. The median (interquartile range) ICU stay was 5.5 (range 4-11.5) days in patients who did and I (range 1-2) day in those who did not develop ARF (P
KW - Coronary artery bypass
KW - Coronary artery diseases
KW - Kidney failure, acute
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M3 - Article
C2 - 17952028
AN - SCOPUS:37249049868
VL - 73
SP - 559
EP - 565
JO - Minerva Anestesiologica
JF - Minerva Anestesiologica
SN - 0375-9393
IS - 11
ER -