Acute renal failure in orthopaedic surgery

Andreas F. Mavrogenis, Evanthia A. Mitsiokapa, Matteo Romantini, Valeria Grandinetti, Luis Coll-Mesa, Pietro Ruggieri, Panayiotis J. Papagelopoulos

Research output: Contribution to journalArticlepeer-review


Orthopaedic diseases affect a broad spectrum of patients, and many of these have concomitant medical problems that may differ from those of the general surgical population. Acute postoperative renal failure is thought to arise secondary to acute tubular necrosis from volume depletion, reduction in glomerular filtration rate, hypotension, and nephrotoxic drugs. If acute renal failure occurs and necessitates hemodialysis, morbidity and mortality are significantly increased. To enhance the literature, we performed this study to review the rates and risk factors for acute renal failure in orthopaedic surgery. This information may be useful for orthopaedic surgeons and treating physicians during the rehabilitation stage, to provide a rationale to stratify a patient's risk of acute renal failure or death on the basis of perioperative medical factors and type of surgery, or for improved perioperative monitoring, better surveillance, and preventive measures to reduce this risk.

Original languageEnglish
Pages (from-to)149-158
Number of pages10
JournalJournal of Long-Term Effects of Medical Implants
Issue number2
Publication statusPublished - 2011


  • Acute renal failure
  • Orthopaedic surgery
  • Risk factors

ASJC Scopus subject areas

  • Biomedical Engineering
  • Dentistry(all)


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