Acute respiratory distress syndrome in adenovirus type 4 pneumonia: A case report

R. Narra, Patrizia Bono, Antonella Zoccoli, Anna Orlandi, S. Piconi, G. Grasselli, Stefania Crotti, Alessia Girello, Antonio Piralla, Fausto Baldanti, Giovanna Lunghi

Research output: Contribution to journalArticlepeer-review


Human adenoviruses (HAdVs) cause a wide spectrum of clinical syndromes, depending on species and types, from mild respiratory infections to deadly pneumonia: in particular, severe infections occur in immunocompromised patients. In this report, we describe the case of a 36 years-old woman admitted to our intensive care unit (ICU) with severe respiratory distress syndrome caused by adenovirus pneumonia, that required invasive respiratory support (mechanical ventilation and extracorporeal membrane oxygenation). Molecular assays detected the virus in respiratory and plasma specimen and sequencing procedure identified HAdV type 4. Patient improved after cidofovir administration. Leukopenia and subsequent bacterial infection occurred, but the patient recovered completely and was discharged from the hospital after 54 days.

Original languageEnglish
Pages (from-to)78-81
Number of pages4
JournalJournal of Clinical Virology
Publication statusPublished - Aug 1 2016


  • Adenoviral pneumonia
  • Adenovirus
  • Infectious disease
  • Intensive care unit
  • Polymerase chain reaction (PCR)

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases


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